Chad A. Livasy, MD : Assistant Professor  
 

Chad A. Livasy, MD

Associate Professor
 
Office: 919-843-1068
E-mail: chad_livasy@med.unc.edu
 
 
 
 
Research Interests
 
My research focus is in the field of breast cancer, in particular, molecular subtyping of breast carcinomas and their pathologic phenotype, origin of estrogen receptor-negative breast cancers, evaluating tumors for targeted therapy, and predicting response to neoadjuvant chemotherapy using molecular markers.
 
Publications
 
Millikan RC, Newman B, Chiu-Kit T, Moorman P, Conway K, Smith LV, Labbok M, Geradts J, Bensen JT, Jackson S, Nyante S, Livasy C, Carey L, Earp HS, Perou CM. 2007. Epidemiology of basal-like breast cancer. Breast Cancer Research and Treatment (in press).
 
Hecht JL, Kliman EN, Allred SM, Pflueger CH, Chang BJ, Doss BJ, Roberts D, Livasy CA, Bhan I, Zambrano E, Ross DW, Senagore, P, Husain SA. 2007. Reference weights for placentas delivered before the 28th week of gestation. Placenta (in press)
 
Rivenbark AG, Livasy CA, Boyd CE, Keppler D, Coleman WB. 2007. Methylation-dependent silencing of cystatin M in primary human breast tumors and metastatic lesions. Experimental and Molecular Pathology (in press).
 
Hecht J, Allred E, Kliman H, Zambrano E, Doss B, Husain A, Pflueger S, Chang C, Livasy C, Roberts D, Bhan I, Ross D, Senagore P, Leviton A. 2007. Histologic characteristics of singleton placentas delivered before the 28th week of gestation. Pathology (in press).
 
Livasy CA, Perou CM, Karaca G, Maia D, Susan Jackson, Chiu-Kit Tse, Millikan R. 2007. Identification of a basal-like subtype of breast ductal carcinoma in situ. Human Pathology 38(2):197-204.
 
Ollila D, Klauber-DeMore N, Tesche L, Kuzmiak C, Pavic D, Goyal L, Lian J, Chang S, Livasy C, Sartor CI. 2007. Feasibility of breast preserving therapy with single fraction in situ radiotherapy delivered intraoperatively. Annals of Surgical Oncology 14(2):660-9.
 
Carey LA, Perou CM, Livasy CA, Dressler LG, Cowan D, Conway K, Karaca G, Troester MA, Tse CK, Edmiston S, Deming AL, Geradts J, Cheang M, Nielson TO, Moorman PG, Earp SH, Millikan RC. 2006. Race, Breast Cancer Subtypes, and Survival in the Carolina Breast Cancer Study. Journal of the American Medical Association 295(21);2492-2502.
 
Hu Z, Fan C, Oh DS, Marron JS, He X, Bahjat F, Qaqish BF, Livasy C, Carey LA, Reynolds E, Dressler L, Nobel A, Parker J, Ewend ME, Sawyer LR, Wu J, Liu Y, Nanda R, Tretiakova M, Orrico AR, Dreher D, Palazzo JP, Perreard L, Nelson E, Mone M, Hansen H, Mullins M, Quackenbush JF, Ellis MJ, Olopade OI, Bernard PS and Perou CM. 2006. The Molecular
Portraits of Breast Tumors Are Conserved Across Microarray Platforms. BioMed Central Genomics 27;7:96.
 
Neuman H, Carey LA, Ollila DW, Livasy C, Calvo BF, Meyer AA, Kim HJ, Meyers MO, Dees EC, Collichio FA, Sartor CI, Moore DT, Sawyer LR, Frank J, and Klauber-DeMore N. 2006. Axillary lymph node count is lower after neoadjuvant chemotherapy. The American Journal of Surgery 191(6):827-9.
 
Klauber-DeMore N, Ollila DW, Moore DT, Livasy C, Calvo B, Kim HJ, Dees EC, Sartor CI, Sawyer LR, Graham M, Carey LA. 2006. Size of residual lymph node metastases following neoadjuvant chemotherapy in locally advanced breast cancer patients is prognostic. Annals of Surgical Oncology 13(5):685-91.
 
Livasy CA, Karaca G, Nanda R, Tretiakova M, Olopade O , Moore D, and Perou C. 2006. Phenotypic evaluation of the basal-like subtype of invasive breast carcinoma. Modern Pathology 19(2):264-71.
 
Livasy CA, Reading FC, Moore DT, Boggess JF, Lininger RA. 2006. EGFR Expression and HER2/neu overexpression/amplification in endometrial carcinosarcoma. Gynecologic Oncology 100(1):101-6.
 
Kaiser-Rogers KA, McFadden DE, Livasy CA, Dansereau J, Jiang R, Knops JF, Lefebvre L, Rao KW, Robinson WP. 2006. Androgenetic/biparental mosaicism causes placental mesenchymal dysplasia. Journal of Medical Genetics 43(2):187-92.
 
Weigelt B, Hu Z, He X, Livasy C, Carey LA, Ewend MG, Glas AM, Perou C, van ‘t Veer LJ. 2005. Molecular portraits and 70-gene prognosis signature are preserved throughout the metastatic process of breast cancer. Cancer Research 65(20):9155-58.
 
Lark AL, Livasy CA, Millikan RC, Tse J, Moore DT, Cowan D, Dressler L, Little D, Craven R and Cance WG. 2005. High FAK expression in invasive breast carcinomas is associated with an aggressive phenotype. Modern Pathology 18(10):1289-94.
 
Conway K, Parrish E, Edmiston SN, Tolbert D, Tse C, Geradts J, Livasy CA, Singh H, Newman B, Millikan RC. 2005. The estrogen receptor alpha A908G(K303R) mutation occurs at a low frequency in invasive breast tumors: results from a population-based study. Breast Cancer Research 7 (6):R871-R880.
 
Lightfoot HM, Lark A, Livasy CA, Moore DT, Cowan D, Dressler L, Craven R, Cance WG. 2004. Upregulation of focal adhesion kinase (FAK) expression in ductal carcinoma in situ (DCIS) is an early event in breast tumorigenesis. Breast Cancer Research and Treatment 88(2):109-16.
 
Nielsen TO, Hsu FD, Jensen K, Cheang M, Karaca G, Hu Z, Hernandez-Boussard T, Livasy C, Cowan D, Dressler L, Akslen LA, Ragaz J, Gown AM, Gilks CB, van de Rijn M, Perou CM. 2004. Immunohistochemical and clinical characterization of the Basal-like subtype of invasive breast carcinoma. Clinical Cancer Research 15;10(16):5367-74.
 
Livasy CA, Moore DT, Van Le L. 2004. The Clinical Significance of a Negative Loop Electrosurgical Cone Biopsy for High-Grade Dysplasia. Obstetrics and Gynecology 104(2):250-254.
 
Livasy CA, Moore DT, Cance WG, Lininger RA. 2004. Focal adhesion kinase (FAK) overexpression in endometrial neoplasia. Applied Immunohistochemistry and Molecular Morphology 12(4):342-345.
 
Hall W, Detterbeck FC, Livasy CA, Fowler WC Jr. 2004. Endobronchial clear cell adenocarcinoma occurring in a patient 15 years after treatment for DES-associated vaginal clear cell adenocarcinoma. Gynecologic Oncology 93(3):708-10.
 
Yang XH, Hand RA, Livasy CA, Cance WG, Craven RJ. 2003. Overexpression of the receptor tyrosine kinase Tie-1 intracellular domain in breast cancer. Tumor Biology 24(2):61-69.
 
Livasy CA, Tishko D, Maygarden SJ. 2003. Miliary pulmonary metastases from a clinically occult pleural mesothelioma: a case report and review of the literature. Annals of Diagnostic Pathology 7(4): 249-253.
 
Lark AL, Livasy CA, Calvo B, Caskey L, Moore DT, Yang X, Cance WG. 2003.
Overexpression of focal adhesion kinase in primary colorectal carcinomas and colorectal liver metastases: immunohistochemistry and real-time pcr analysis. Clinical Cancer Research 9(1): 215-222.
 
Livasy CA, Woosley JT. 2003. Solitary nasal ala nodule in a young woman. Cellular neurothekeoma. Archives of Dermatology 139(4): 531-536.
 
Kazachkov MY, Muhlebach MS, Livasy CA, Noah TL. 2001. Lipid-laden macrophage index and inflammation in bronchoalveolar lavage fluids in children. European Respiratory Journal 18(5): 790-795.
 
Pisano ED, Johnston RE, Chapman D, Geradts J, Iacocca M, Livasy CA, Washburn D, Sayers D, Zhong Z, Kiss M, Thomlinson WC. 2000. Human breast cancer specimens: Diffraction enhanced imaging with histologic correlation-improved conspicuity of lesion detail compared with digital radiography. Radiology 214 (3): 895-901.
 

Sidler AK, Huston BM, Livasy CA, Thomas DB. 2000. Pathologic case of the month: Eosinophilic granuloma (Langerhans cell histiocytosis). Archives of Pediatric Adolescent Medicine 154: 1057-1058.

 

Livasy CA, Maydarden SJ, Rajaratnam CT, Novotny DB. 1999. Predictors of recurrent dysplasia after a cervical loop electrocautery excision procedure for CIN-3: a study of margin, endocervical gland and quadrant involvement. Modern Pathology 12 (3): 233-238.

 
Kaplan AM, Creager AJ, Livasy CA, Boggess J, Dent G. 1999. Intra-abdominal embryonal rhabdomyosarcoma in an adult. Gynecologic Oncology 74: 282-285.
 
Livasy CA, Kaplan AM. 1997. Ciprofloxacin-induced toxic epidermal necrolysis: a case report. Dermatopathology 195: 173-175.
 
 
List of publications from PubMed