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Lisa Jacobs Weinstein, MD

Assistant Professor
 
Office: 919-843-1093
E-mail: lisa_weinstein@med.unc.edu
 
 
 
 
Research Interests
 
My research interests include translational investigation and the application of developing technologies from both the clinical setting and the laboratory. These endeavors have been primarily in the areas of head and neck, genitourinary and thyroid pathology. My clinical interests include gastrointestinal pathology, thyroid and head and neck pathology, and fine needle aspiration cytology with emphasis on head and neck and thyroid disease.
 
Selected Publications
 
Haddad RI, Weinstein LJ, Wieczorek TJ, Bhattacharya N, Raftopoulos H, Oster MW, Zhang X, Latham VM Jr, Costello R, Faucher J, DeRosa C, Yule M, Miller LP, Loda M, Posner MR, Shapiro GI. A phase II clinical and pharmacodynamic study of E7070 in patients with metastatic, recurrent, or refractory squamous cell carcinoma of the head and neck: modulation of retinoblastoma protein phosphoryaltion by a novel chloroindolyl sulfonamide cell cycle inhibitor. Clin Cancer Res, 2004 Jul 15;10(14):4680-7.
 
Graner E, Tang D, Rossi S, Baron A, Migita T, Weinstein LJ, Lechpammer M, Huesken D, Zimmerman J, Signoretti S, Loda M. The isopeptidase USP2a regulates the stability of fatty acid synthase in prostate cancer. Cancer Cell, 2004 Mar;5(3):253-261.
 
Rossi S, Graner E, Febbo P, Weinstein L, Bhattacharya N, Onody T, bubley G, Balk S, Loda M. Fatty acid synthase expression defines distinct molecular signatures in prostate cancer. Mol Cancer Res, 2003 Aug;1(10):707-715.
 
Hecht JL, Pinkus JL, Weinstein LJ, Pinkus GS. The value of thyroid transcription factor-1 in cytologic preparations as a marker for metastatic adenocarcinoma of lung origin. Laboratory Investigation, January, 2001.
 
Liu B, LaRose I, Weinstein LJ, Ahn M, Weinstein MH, Richie JP. Expression of telomerase subunits in normal and neoplastic prostate epithelial cells isolated by laser capture microdissection. Surgical Forum, 2000;L1:619-621.
 
Valentino J, Weinstein LJ, Rosenblum R, Regine W, and Weinstein MH. Radiation and intra-arterial cisplatin: Effects on arteries and free tissue transfer. Arch Otolaryngol Head Neck Surg,2000;126:215-219.
 
Weinstein LJ, Ain KB. Primary thyroid lymphoma: a comprehensive assessment and clinical approach. The Endocrinologist 1999;9:45-51.
 
Jacobs LB, Epstein JI, Westra WH. Image analysis of skin specimens: the application of telepathology to frozen section evaluation. Hum Pathol 1997;28(1):30-5.
 
Jacobs LB, McCarthy EF. Ki-67 immunostaining as a tool in the diagnosis of central cartilage lesions. Iowa Orthop J 1996;16:39-45.
 
Kuhajda FP, Jenner K, Wood FD, Hennigar RA, Jacobs LB, Dick JD, Pasternack GR. Fatty acid synthesis: A potential selective target for antineoplastic therapy. Proc Natl Acad Sci 1994;91:6379-83.