Devon Risher
B.S., Biological Science
Smith College
Northampton, MA

Robert H. Wagner Scholar
in Molecular and Cellular Pathology
I am currently in my second year in the Molecular and Cellular Pathology program, and came to UNC because of my interest in cancer research. I grew up in sunny Ft. Myers, FL although I am happy now to be living in a state with a change of seasons! I received my bachelor’s degree in biological sciences from Smith College, Northampton, MA in May of 2004. While at Smith, I completed a minor in geology, traveling to places of natural wonder like Death Valley, CA. My honors thesis involved DNA sequence analysis of a number of dusky salamander populations, with the hope of better characterizing cryptic species. I joined the graduate program at UNC in Fall 2004. My first rotation was in the laboratory of Dr. Frank C. Church, where my rotation project  focused on the migration and adhesion capabilities of three kidney tumor cell types. I also rotated in the lab of Dr. David G. Kaufman, where I looked at mTOR signaling in endometrial stromal cells.  I joined the lab of William B. Coleman in May of 2005 and have begun working on a project investigating the CpG island methylator phenotype (CIMP) in the context of breast cancer. In the few years since CIMP first was described in colorectal cancer, it has been found in ovarian, gastric, liver, kidney, and pancreatic tumors as well as leukemias, lymphomas, and neuroblastomas. Our objectives are to determine if CIMP occurs in breast cancer and to identify the preferentially methylated genes in this tumor system.

When not busy in lab I enjoy decorating my apartment a la Martha Stewart, spoiling the sweetest cat in the world, Elle, and exploring my new home state. I’m also a movie buff and hockey fan (Go Everblades!)

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