Predoctoral and Postdoctoral Training in
Environmental Pathology
Department of Pathology and Laboratory Medicine
University of North Carolina School of Medicine
Chapel Hill, NC

     

Environmental Pathology
Publications by Predoctoral Trainees

2004
Gray, D.R., Huss, W.J., Yau, J.M., Durham, L.E., Werdin, E.S., Funkhouser, Jr., W.K., and Smith, G.J. (2004)  Short-term human prostate primary xenografts: An in vivo model of human prostate cancer vasculature and angiogenesis.  Cancer Research 64:1712-1721.

Huss, W.J., Gray, D.R., Werdin, E.S., Funkhouser, Jr., W.K., and Smith, G.J. (2004) Evidence of pluripotent human prostate stem cells in a human prostate primary xenograft model. The Prostate (In Press).

Ryan, J.L., Fan, H., Swinnen, L.J., Schechman, S.A., Raab-Traub, N., Covington, M., Elmore, S., and Gulley, M.L. (2004) Epstein-Barr virus (EBV) DNA in plasma is not encapsidated in patients with EBV-related malignancies.  Diagnostic Mol. Pathol. (In Press).

Whitley, B.R., Palmieri, D., Twerdi, C., and Church, F.C. (2004) Expression of active plasminogen activator inhibitor-1 reduces cell migration and invasion in breast and gynecologic cancer cells.  Exp. Cell Res. (In Press).

2003
Deming, P.B., Flores, K.G., Downes, C.S., Paules, R.S., and Kaufmann, W.K. (2003) ATR enforces the topoisomerase II-dependent G2 checkpoint through inhibition of Plk1 kinase. J. Biol. Chem. 277:36832-36838. 

Furmaga, W.B., Ryan, J., Coleman, W.B., Cole, S.R., and Tsongalis, G.J. (2003) Alu-Profiling of primary and metastatic non-small cell lung cancer. Exp. Mol. Pathol. 74:224-229.

Hoffman, M., Loh, K.L., Bond, V.K., Palmieri, D., Ryan, J.L., and Church, F.C. (2003) Localization of heparin cofactor II in injured human skin: A potential role in wound healing. Exp. Mol. Pathol. 75:109-118.

Jahn, J.E., Ricketts, S.L., and Coleman, W.B. (2003)  Identification of candidate liver tumor suppressor genes from human 11p11.2 by transcription mapping of microcell hybrid cell lines.  Int. J. Oncol. 22:1303-1310.

Kaufmann, W.K., Heffernan, T.P., Beaulieu, L.M., Doherty, S., Frank, A.R., Zhou, Y., Bryant, M.F., Zhou, T., Luche, D.D., Nikolaishvilli-Feinberg, N., Simpson, D.A., and Cordeiro-Stone, M. (2003) Caffeine and human DNA metabolism: The majic and the mystery. Mutation Research 532:85-102.

Ricketts, S.L., Carter, J.C., and Coleman, W.B. (2003) Identification of three 11p11.2 candidate liver tumor suppressors through analysis of known human genes.  Mol. Carcinogenesis 36:90-99.

2002
Arnold, J.T., Lessey, B.A., Seppala, M., and Kaufman, D.G. (2002) Effect of normal endometrial stroma on growth and differentiation in Ishikawa endometrial adenocarcinoma cells. Cancer Res. 62:79-88.

Deming, P.B., Flores, K.G., Downes, C.S., Paules, R.S., and Kaufmann, W.K. (2003) ATR enforces the topoisomerase II-dependent G2 checkpoint through inhibition of Plk1 kinase. J. Biol. Chem. 277:36832-36838.

Heffernan, T.P., Simpson, D.A., Frank, A.R., Heinloth, A.N., Paules, R.S., Cordiero-Stone, M., and Kaufmann, W.K. (2002) An ATR- and Chk1-dependent S checkpoint ibhibits replicon initiation following UVC-induced DNA damage.  Mol. Cell. Biol. 22:8552-8561.

Kaufmann, W.K., Campbell, C.B., Simpson, D.A., Deming, P.B., Filatov, L., Galloway, D.S., Zhao, X.J., Creighton, A.M., and Downes, C.S. (2002) Degradation of ATM-independent decatenation checkpoint function in human cells is secondary to inactivation of p53 and correlated with chromosomal destabilization.  Cell Cycle 1:323-330.

Palmieri, D., Lee, J.-W., Juliano, R.L., and Church, F.C. (2002) Expression of plasminogen activator inhibitor-type 1 and 3increase cell adhesion and motility of MDA-MB-435 cancer cells. J. Biol. Chem. 277:40950-40957.

Ricketts, S.L., Garcia, N.F., Betz, B.L., and Coleman, W.B. (2002) Identification of candidate liver tumor suppressor genes from human 11p11.2-p12. Genes Chromosomes Cancer 33:47-59.

Rider, M.A., Butz, G.M., Ricketts, S.L., Newberry, S.T., Grisham, J.W., and Coleman, W.B. (2002) Suppression of tumorigenicity in rat liver tumor cells by human chromosome 13: Evidence against the involvement of pRb and BRCA2. Int. J. Oncol. 20:235-245.

2001
Arnold, J.T., Kaufman, D.G., Seppala, M., and Lessey, B.A. (2001) Endometrial stromal cells regulate epithelial cell growth in vitro: a new co-culture model. Human Reprod. 16:836-845.

Bullock, S.K., Kaufmann, W.K., and Cordiero-Stone, M. (2001) Enhanced S phase delay and inhibition of replication of an undamaged shuttle vector in UVC-irradiated xeroderma pigmentosum variant.  Carcinogenesis 22:233-244.

Deming, P.B., Cistulli, C.A., Zhao, H., Graves, P.R., Piwnica-Worms, H., Paules, R.S., Downes, C.S., and Kaufmann, W.K. (2001) The human decatenation checkpoint. Proc. Natl. Acad. Sci. U.S.A. 98:12044-12049.

2000
Bushman, J.E., Palmieri, D., Whinna, H.C., and Church, F.C. (2000) Insight into the mechanism of asparaginase-induced depletion of antithrombin III in treatment of childhood acute lymphoblastic leukemia.  Leukemia Research 27:559-565.
1999
Coleman W.B., Ricketts S.L., Borchert K.M., Presnell S.C., Esch G.L., McCullough K.D., Weissman B.E., Smith G.J., and Grisham J.W. (1999) Induction of rat WT1 gene expression correlates with human chromosome 11p11.2-p12-mediated suppression of tumorigenicity in rat liver epithelial tumor cell lines. International Journal of Oncology 14:957-963.

Lyons-Darden, T. and Topal, M.D. (1999) Effects of temperature, Mg2+ concentration and mismatches on triplet-repeat expansion during DNA replication in vitro. Nucleic Acids Research 27:2235-2240.

Lyons-Darden, T. and Topal, M.D. (1999) Abasic sites induce triplet-repeat expansion during DNA replication in vitro. Journal of Biological Chemistry 274:25975-25978.

Palmieri, D., Watson, J.M. and Rinehart, C.A. (1999) Age-related expression of PEDF/EPC-1 in human endometrial stromal fibroblasts: Implications for interactive senescence. Experimental Cell Research 247:142-147.

Rinehart, C.A., Watson, J.M., Torti, V.R., and Palmieri, D. (1999) The role of IL-1 in interactive senescence and age-related human endometrial cancer. Experimental Cell Research 248:599-607.

1998
Kazantsev, A., Bullock, S.K., Sancar, A., and Cordiero-Stone, M. (1998) Generation and characterization of an immortal cell line of xeroderma pigmentosum group E.  Mutation Research 407:55-65.

McCullough, K.D., Coleman, W.B., Ricketts, S.L., Wilson, J.W., Smith, G.J., and Grisham, J.W. (1998) Plasticity of the neoplastic phenotype in vivo is regulated by epigenetic factors. Proceedings of the National Academy of Sciences USA 95:15333-15338.

1997
Crider-Miller, S.J., Reid, L.H., Higgins, M.J., Nowak, N.J., Shows, T.B., Futreal, P.A., and Weissman, B.E. (1997) Novel transcribed sequences within the BWS/WT2 region in 11p15.5: tissue-specific expression correlates with cancer type. Genomics 46:355-363. 

Kaufmann, W.K., Byrd, L.L., Palmieri, D., Nims, R.W. and J.M. Rice (1997) TGF-a sustains clonal expansion by promoter dependent, chemically initiated rat hepatocytes.Carcinogenesis 18:1381-1387. 

Reid, L.H., Davies, C., Cooper, P.R., Crider-Miller, S.J., Sait, S.N., Nowak, N.J., Evans G., Stanbridge, E.J., deJong, P., Shows, T.B., Weissman, B.E., and Higgins, M.J. (1997) A 1-Mb physical map and PAC contig of the imprinted domain in 11p15.5 that contains TAPA1 and the BWSCR1/WT2 region. Genomics 43:366-375. 

Reinhart, C.A., and Torti, V.R. (1997) Aging and cancer: The role of stromal interactions with epithelial cells.  Molecular Carcinogenesis 18:187-192. 

1996
Orlow, I., Iavarone, A., Crider-Miller, S.J., Bonilla, F., Latres, E., Lee, M.H., Gerald, W.L., Massague, J., Weissman, B.E., and Cordon-Cardo, C. (1996) Cyclin-dependent kinase inhibitor p57KIP2 in soft tissue sarcomas and Wilms' tumors. Cancer Res. 56:1219-1221.

Reid, L.H., Crider-Miller, S.J., West, A., Lee, M.H., Massague, J., and Weissman, B.E. (1996) Genomic organization of the human p57KIP2 gene and its analysis in the G401 Wilms' tumor assay. Cancer Res. 56:1214-1218.

1995
(Bullock) King, S.A., Wilson, S.J., Farber, R.A., Kaufmann, W.K., and Cordeiro-Stone, M. (1995) Xeroderma pigmentosum variant: Generation and characterization of fibroblastic cell lines transformed with SV40 large T antigen. Experimental Cell Research 217:100-108.

Department of Pathology and Laboratory Medicine
Graduate and Post-Graduate Training in Molecular and Cellular Pathology
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Comments to Dr. William B. Coleman