Graduate Studies in
Molecular and Cellular Pathology
Department of Pathology and Laboratory Medicine
University of North Carolina School of Medicine
Chapel Hill, North Carolina
     
Providing a unique environment for graduate training in experimental pathology...

Molecular and Cellular Pathology
Course Offerings

 
This page provides a brief description of courses offered by the Molecular and Cellular Pathology Graduate Program, and the faculty of the Department of Pathology and Laboratory Medicine.  Courses that are infrequently offered are not listed.  A complete listing of courses offered by the Department of Pathology and Laboratory medicine can be found in the Graduate School Record, under Pathology.
Courses for Graduate Students and Advanced Undergraduates
PATH 006E History of Disease (3 Hours).  This course is focused on plagues and people.  It presents an introduction to the social history of plagues and the motif of plagues in a variety of contemporary and historical writing.  This course provides an opportunity for students to read and respond to works presented as historical, fictional, and scientific writing.  First-year undergraduate seminar course.  Offered Spring semester.  Instructor: H.M. Reisner.
PATH 128 Biology of Human Disease (Biology 008; 3 Hours).  This course presents an overview of basic human molecular and cellular biology in the setting of common human diseases.  The course emphasizes how an understanding of disease mechanisms provides the knowledge base for informed use of modern health care.  BA-level and General College-level natural science.  Open to all undergraduates and graduates.  No prerequisites.  Offered Fall semester.  Instructors: H.M. Reisner.
PATH 426 Biology of Blood Diseases (Biology 134; 3 Hours).  An introduction to the biology and pathophysiology of blood and the molecular mechanisms of some human diseases, including malignant neoplasms, anemias, hemophilias, thrombophilias, artheroschlerosis, and viral infections.  Prerequisite: Biology 52 or permission of the instructor.  Offered Fall semester.  Instructor: F.C. Church.
PATH 462 Experimental Pathology (Hours, credits, and instructor to be arranged on an individual basis).  This course involves hands-on research experience in a predetermined instructor's laboratory.  Students have the opportunity to learn and apply specific techniques, and to participate in investigations of molecular mechanisms responsible for disease processes (pathobiology).  This course may be repeated for credit.  Instructors: Staff.
PATH 463 Electron Microscopy (4 Hours).  This course covers both theoretical and practical aspects of electron microscopy, including application of transmission and scanning electron microscopy to the pathological assessment of cells and tissues, with emphasis on evaluation of the ultrastructure of cells and organelles.  Two hous of lecture and six hours of laboratory per week.  Prerequisite: Permission of instructor.  Offered Fall semester.  Instructor: C.R. Bagnell, Jr.
PATH 464 Light Microscopy (3 Hours).  This course focuses on practical fundamentals of light microscopy, including optics, contrast mechanisms, fluorescence, laser scanning confocal microscopy, photography, and digital imaging.  Prerequisite: Permission of instructor.  Offered Spring semester.  Instructor: C.R. Bagnell, Jr.
PATH 678 Human DNA Metabolism (2 Hours).  This course examines the molecular biology of DNA replication, resorption, recombination, and repair as these processes occur in human cells.  Prerequisite: A basic biochemistry course.  Offered Fall semester (alternative years).  Instructor: W.K. Kaufmann.
Courses for Graduate Students
PATH 713 Mechanisms of Disease (3 Hours).  A graduate course on cell injury and pathogenesis of disease with emphasis on basic mechanisms at the molecular, cellular, and organismal levels.  Prerequisite: None.  Three hours lecture and 2.5 hours laboratory each week.  Offered Fall semester.  Course Director: F.C. Church.
PATH 714 Mechanisms of Disease Laboratory (2 Hours).  A graduate laboratory course on cell injury and pathogenesis of disease featuring microscopic and gross pathology specimens.  Prerequisite: Pathology 713.  Can be taken concurrently with Pathology 713.  Three hours laboratory each week.  Offered Fall semester.  Course Director: V.L. Godfrey.
PATH 715 Systemic Pathology(3 Hours).  A graduate course on the pathology and pathophysiology of disease with an emphasis on molecular and cellular mechanisms of disease in organ systems.  Prerequisite: Pathology 713.  Three hours lecture each week.  Offered Spring semester.  Course Director: W.B. Coleman.
PATH 716 Systemic PathologyLaboratory (2 Hours).  A graduate laboratory course on pathogenesis of disease of organ systems featuring microscopic and gross pathology specimens.  Prerequisite: Pathology 715.  Can be taken concurrently with Pathology 715.  Three hours laboratory each week.  Offered Spring semester. 
Course Director: V.L. Godfrey.
PATH 723 Special Methods in Pathology (2 Hours).  This course is conducted on a tutorial basis, with the aim of providing experience with specialized laboratory techniques in pathology, including histochemistry, electron microscopy, fluorescent and phase microscopy, chromatography, electrophoresis, and ultracentrifugation.  Prerequisite: Permission of instructor.  Two seminar hours per week.  Offered Spring semester (even numbered years).  Course Director: H.C. Whinna.
PATH 725 Cancer Pathology (3 Hours).  This course examines pathobiological features of cancer.  An interdiciplinary approach draws from epidemiology, genetics, molecular biology, and clinical medicine to investigate cancer etiology, pathogenesis, prevention, and treatment.  Prerequisite: Permission of instructor.  Three lecture hours per week, optional 2 hour laboratory per week.  Instructor: W.K. Kaufmann.
PATH 792 Seminar in Carcinogenesis (Toxicology 292; 2 Hours).  This course surveys classical and current literature on selected critical issues in carcinogenesis, focusing on the molecular pathogenesis of cancer pathogenesis in .  Students discuss experimental methods and observations, as well as theories and generalizations.  Offered Spring semester.  Instructor: W.B. Coleman.
PATH 801 Seminar in Pathology (2 Hours).  This course emphasizes the development of written and oral scientific communication skills.  It is designed specifically for first-year and second-year pathology graduate students.  This course may be repeated.  Offered Fall semester.  Instructor: M. Cordeiro-Stone.
PATH 900 Research in Pathology (2-12 Hours).  This is a research course in which advanced students in pathology carry on investigations on mechanisms of disease.  Six or more laboratory hours per week.  May be repeated.  Offered Fall and Spring semesters, and Summer sessions.  Instructors: Staff.
PATH 994 Doctoral Dissertation (Hours/credits vary).  May be repeated.  Offered Fall and Spring semesters, and Summer sessions.  Instructors: Staff.

Comments to Dr. William B. Coleman