UNC Department of Pathology and Laboratory Medicine
Graduate Student Webpage
Complete Alphabetic Listing of Graduates of the Program in
Molecular and Cellular Pathology
1954-Present
A
Dolph Oliver Adams, M.D., Ph.D., 1972
Dissertation title:  The Differentiation of Mononuclear Phagocytes In Vivo: A Correlated Histologic and Fine Structural Study
Advisor:  Kenneth M. Brinkhous

Michael Altenburg, Ph.D., 2007
Dissertation title:  Atherosclerotic Mechanisms of Apolipoprotein E Isoforms
Advisor: Nobuyo Maeda
Current Position:  Postdoctoral Research Fellow, Department of Pathology and Laboratory Medicine, University of North Carolina School of Medicine, Chapel Hill, NC
Email: michael.altenburg@pathology.unc.edu

Julia T. Arnold, Ph.D., 1998
Dissertation title: Human Endometrial Stromal Cells Regulate Epithelial Cell Growth and Function In Vitro
Advisor: David G. Kaufman
Current Position: Staff Scientist, National Center for Complementary and Alternative Medicine, National Institutes of Health, 
Bethesda, MD
Email:  jarnold@mail.nih.gov
URL: http://nccam.nih.gov/

Joshua M. Astern, Ph.D., 2007
Dissertation title:  Myeloperoxidase in Vascular Disease and Autoimmunity
Advisor: Ronald J. Falk
Current Position:  Postdoctoral Research Fellow, Department of Pathology and Laboratory Medicine, University of North Carolina School of Medicine, Chapel Hill, NC
Email: joshua.astern@pathology.unc.edu

B
Mary S. Baker, M.S., 1982
Thesis title:  Alkylation of Deoxyribonucleotides and Their Role in Mutagenesis
Advisor:  Michael D. Topal

Linda L. Barrett, M.S., 1990
Thesis title: Five-Azacytidine Treatment Increases Anchorage Independent Growth of Human Endometrial Stromal Cells Expressing SV40 Large T Antigen
Advisor: David G. Kaufman

Mohammed BaSalamah, Ph.D., 2000
Dissertation title: Testican: Novel Human Gene Product
Advisor: Cora-Jean S. Edgell
Current Position: Head, Department of Pathology, Umm Al-Qura University, Makkah, Saudi Arabia
E-mail:  basalamah1@uqu.edu.sa

Roc Bauman, M.S., 1988
Thesis title:  Atherosclerosis in Hypercholesteerolemic Normal and von Willenrand's Disease Swine
Advisor:  Thomas R. Griggs

Susannah Jo Bauman, Ph.D., 1999
Dissertation title: Antithrombotic Properties of Heparin Cofactor II
Advisor: Frank C. Church
Email: bauman@shasta.com

Lea M. Beaulieu, Ph.D., 2007
Dissertation title:  Role of the Protein C System in Breast Cancer Cell Invasion and Endothelial Cell Angiogenesis
Advisor: Frank C. Church
Current Position:  Postdoctoral Fellow, Multidisciplinary Training in Cardiovascular Research at the Whitaker Cardiovascular Institute, Dept of Medicine, School of Medicine, Boston University Medical Center, Boston, MA
Email:  lmb@bu.edu

Cynthia Irvin Behe, M.S., 1999
Thesis title:  Defective Cell Cycle Checkpoint Function in Transformed Hepatocytes and WB-F344 Hepatic Epithelial Stem-like Cells
Advisor: William K. Kaufmann
Current Position: Reserch Technician, Department of Pharmacology, University of North Carloina, Chapel Hill, NC
E-mail: mcirvin@med.unc.edu

William Patrick Bennett, M.S., 1981
Thesis title:  The Effects of an Extracellular Protease From Serratia marcescens on Membrane Functions of Human Platelets Advisor:  Herbert A. Cooper

Karen Louise S. Bentley, Ph.D., 1985
Dissertation title:  Cell Cycle-related Genotoxic Effects of 4-Nitroquinoline-1-oxide in C3H 10T1/2 Cells
Advisor:  Joe W. Grisham

D. Hunter Best, Ph.D., 2007
Dissertation title:  Liver Regeneration by Small Hepatocyte-like Progenitor Cells After Hepatotoxic and Necrotic Injury in Fischer 344 Rats 
Advisor: William B. Coleman
Current Position:  Clinical Fellow, Molecular Genetics Laboratory, Vanderbilt University Medical Center, Nashville, TN
Email: hunter.best@vanderbilt.edu

Bryan L. Betz, Ph.D., 2002
Dissertation title: The hSNF5/INI1 Tumor Suppressor Gene: Mutational Analysis and Functional Characterization
Advisor: Bernard E. Weissman
Current Position: Assistant Professor, Technical Director of the Molecular Diagnostics Laboratory, Department of Pathology, University of Michigan Medical School, Ann Arbor, MI
Email: bbetz@med.umich.edu

Sharon Ricketts Betz, Ph.D., 2002
Dissertation title: Identification and Characterization of Candidate Liver Tumor Suppressor Genes from Human Chromosome 11p11.2-p12
Advisor: William B. Coleman
Current Position: Assistant Professor, Assistant Director of the Cytogenetics and Molecular Diagnostics Laboratories, Department of Pathology, University of Michigan Medical School, Ann Arbor, MI
Email: sbetz@med.umich.edu

Terry L. Blakenship-Paris, D.V.M.,Ph.D., 1993
Dissertation title:Clostridium difficile Enterocolitis Associated With an Atherogenic, High Fat Diet in Hamsters
Advisor: Jerjang Chang

Arthur Palfrey Bode, Ph.D., 1982
Thesis title:  Platelet Factor One in Human Platelets
Advisor:  Fred Dombrose

Mark Gregory Bolyard, Ph.D., 1989
Dissertation title:  Characterization of Subunits of Human Fibrinogen Expressed in Escherichia coli
Advisor:  Susan T. Lord

Sharon King Bullock, Ph.D., 1999
Dissertation title: UV-Induced Inhibition of DNA Replication
Advisor: Marila Cordeiro-Stone
Current Position: Instructor, Medical College of Virginia, Virginia Commonwealth University, Richmond, VA
E-mail:skbulloc@hscvcu.edu
URL: http://views.vcu.edu/mcvro/

C
Russell C. Cattley, M.S., V.M.D., Ph.D., 1988
Thesis title:  Peroxisome Proliferator Hepatocarcinogenesis in Rats
Advisor:  James A. Popp
Current Position: Amgen
E-mail: rcattley@amgen.com

Jingjing Chai, Ph.D., 2005
Dissertation title:  Identification of the Signal Transduction Pathway and Functional Domains of hSNF5 in Human Rhabdoid Tumor Cell Line and Mouse Rhabdoid Tumors
Advisor: Bernard E. Weissman
Current Position:  Postdoctoral Research Fellow, Department of Pathology and Laboratory Medicine, University of North Carolina School fo Medicine, Chapel Hill, NC
Email: jingjing.chai@pathology.unc.edu

Linda A. Charles, Ph.D., 1991
Dissertation title: The Reactivity and Pathogenicity of Anti-Neutrophil Cytoplasmic Autoantibodies
Advisor: J. Charles Jennette
Current Position: Scientist, Quintiles, Inc., Durham, NC

Ronald Kent Charlton, Ph.D., 1979
Dissertation title:  An Investigation of the Loss of Cytochrome P-450 From Cultured Hepatocytes
Advisor:  Joe W. Grisham

Pengchin Chen, Ph.D., 1992
Dissertation title: Mapping of Tumor Suppressor Genes in Soft Tissue Sarcoma Cell Lines by Functional Analyses
Advisor: Bernard E. Weismann
Current Position: Assistant Research Molecular Epidemiologist, Department of Epidemiology and Biostatistics, School of Medicine, University of California-San Francisco
E-mail: pengchin@epi.ucsf.edu
URL: http://chanane.ucsf.edu/epidem/personnel/pchen.html

Chia Chiao, Ph.D., 1994
Dissertation title:Mechanisms of Promotion of Hepatocarcinogenesis in vitro
Advisor: William K. Kaufmann

Cheryl A. Cistulli, Ph.D., 2000
Dissertation title: Cell Cycle Checkpoints and Human Carcinogenesis
Advisor: William K. Kaufmann
Current Position: Postdoctoral Fellow, Laboratory of Structural Biology, National Institute of Environmental Health Sciences, NIEHS, Research Triangle Park, NC 
Email: cistulli@niehs.nih.gov
URL: http://dir.niehs.nih.gov/dirlsb/home.htm

Adella R. Clark, M.S., 1994
Thesis title: Immunogenetics of Inhibitor Response to FVIII:C
Advisor: Howard M. Reisner

George Elton Cox, M.D., M.S., 1954
Thesis title:  Cholesterol in Atheroschlerosis: Studies on its Biosynthesis
Advisor:  C. Bruce Taylor

Shyra J. Crider-Miller, Ph.D., 1998
Dissertation title: Identification of Candidate Pediatric Tumor Suppressor Genes on Human Chromosome 11p15.5
Advisor: Bernard E. Weissman
Current Position: Postdoctoral Fellow, Department of Cell Biology, Neurobiology, and Anatomy, University of Cincinnati, Cincinnati, OH
E-mail: milss@email.uc.edu

Tracey Dawson Cruz, Ph.D., 1999
Dissertation title: Chemokine Receptors in Inflammatory Disease: Studies Using Chemokine Receptor Knockout Mice
Advisor: Nobuyo N. Maeda
Current Position:  Assistant Professor, Forensic Science Program, Department of Biology, Medical College of Virginia, Virginia Commonwealth University, Richmond, VA
Email:  tcdawson@vcu.edu
URL:  http://www.has.vcu.edu/bio/

D
Paul deVendel Davis, J.D., M.S.
Thesis title: The Heterozygote for Hemophilia A and B: A Coagulation and Genetic Study
Advisor:  Kenneth M. Brinkhous

Jessica N. DelBove, Ph.D., 2007
Dissertation title:  Characterization of the Tumor Suppressor Capabilities of SWI/SNF Complex Member BAF155 in Cancer Cell Lines and Cooperation of SNF5 and p53 Pathways
Advisor: Bernard E. Weissman
Current Position:  Postdoctoral Research Fellow, Department of Pathology and Laboratory Medicine, University of North Carolina School of Medicine, Chapel Hill, NC
Email: jessica.delbove@pathology.unc.edu

Paula B.Deming, Ph.D., 2002
Dissertation title: Mechanisms of Human Decatenation Checkpoint Function
Advisor: William K. Kaufmann
Current Position: Postdoctoral Fellow, Department of Pathology, University of Vermont, Burlington, VT
Email: Paula.Deming@med.uvm.edu

Ernesto A. deVeyra, Jr., M.D., M.S., 1965
Thesis title:  Nerve Fiber Lesions in the Brain Stem Following Head Injury
Advisor:  Margaret C. Swanton

Laura A. DiMichele, Ph.D., 2007
Dissertation title:  Focal Adhesion Kinase in Cardiac Development and Disease 
Advisor: Joan M. Taylor
Current Position:  Postdoctoral Research Fellow, Department of Pathology and Laboratory Medicine, University of North Carolina School of Medicine, Chapel Hill, NC
Email:  laura.dimichele@pathology.unc.edu

John James Dino, Jr., Ph.D., 1988
Dissertation title: Characterization of Radioactive "Early-eluting" Chromatographic Material Resulting from Interactions of Tritiated Benzo[a]pyrene With Liver Nucleic Acids in A/HeJ Female Mice
Advisor: David G. Kaufman

Norman A. Doggett, Ph.D., 1986
Dissertation title:  The Temporal Order of Replication of Protooncogenes in Synchronized C3H 10T1/2 Cells
Advisor:  David G. Kaufman
Current Position: Chief Scientist, Center for Human Genome Studies, Bioscience Division, Los Alamos National Laboratory, Los Alamos, NM
E-mail: doggett@lanl.gov
URL: http://bdiv.lanl.gov/ and http://www.lanl.gov/worldview/organization/profiles/b_profile.shtml

Margaret M. Doherty, M.S., 1994
Thesis title: Regulation of the Epidermal Growth Factor Receptor in Rat Tracheal Epithelial Cells
Advisor: Paul Nettesheim

Bruce Hugh Dorman, Jr., Ph.D., 1982
Dissertation title:  Chemical Carcinogen Effects on Human Endometrium In Vitro: Phenotypic Alterations in Cell Cultures and Carcinogen Binding to DNA in organ Cultures
Advisor: David G. Kaufman

E
F
Robert A. Farrell, M.D., M.S., 1957
Thesis title:  A Study of Some Tosyl-Arginine and Acetyl-Tyrosine Esterases and Their Relationship to the Coagulation of Blood
Advisor:  Penick

Leah D. Fletcher, Ph.D., 1993
Dissertation title: Cloning and Characterization of Rat Derived Pneumocystis carinii Genes
Advisor: Christine C. Dykstra

Phillip (Andy) Futreal, Ph.D., 1993
Dissertation title: Physical Mapping of Tumor Suppressor Genes on Human Chromosomes 1q and 17q
Advisor: J. Carl Barrett
Current Position: Research Investigator, The Cancer Genome Project, The Wellcome Trust Sanger Institute, Hinxton, Cambridge, UK
E-mail: paf@sanger.ac.uk
URL: http://www.sanger.ac.uk/

G
Bharat R. Gandhi, M.S., 1984
Thesis title:  Production of Monoclonal Antibodies and Their Use in Characterization of Antigenic Proteins of Toxoplasma gondii Tachyzoites
Advisor:  G. Yancey Gillespie

Jeffrey Bruce Garris, M.S., 1986
Thesis title: Purified Human Factor VIII Procoagulant Protein: Comparative Hemostatic Response After Infusions into Hemophilic and von Willebrand Disease Dogs
Advisor: Kenneth M. Brinkhous

Jennifer Bushman Gilner, Ph.D., 2007
Dissertation title:  Enrichment of Therapeutic Hematopoietic Stem Cell Populations From Embryonic Stem Cells
Advisor: Suzanne Kirby
Current Position:  Medical Student, University of North Carolina School of Medicine, Chapel Hill, NC
Email:  jennifer.gilner@pathology.unc.edu

Laura L. (Neese) Glasscock, Ph.D., 1997
Dissertation title: Protein C Inhibitor: Structure-Activity Relationships and Pathobiological Aspects
Advisor: Frank C. Church
Current Position: Assistant Professor, Department of Biology, Winthrop University, Rock Hill, SC, and Assistant Director of Urology Research, Cannon Research Center, Carolinas Hospital, Charlotte, NC
E-mail: glasscockl@winthrop.edu
URL: http://www.winthrop.edu/biology/facstaff/glasscock.htm

Gavin J. Gordon, Ph.D., 2000
Dissertation title: Characterization of the Cellular Responses During Liver Regeneration in Retrorsine-exposed Rats and Identification of a Novel Hepatic Progenitor Cell
Advisor: William B. Coleman
Current Position: Assistant Professor, Division of Thoracic Surgery, Co-Director, Thoracic Surgery Oncology Laboratory, Brigham and Women's Hospital, Harvard Medical School, Dana-Farber/Harvard Cancer Center, Boston, MA
Email: ggordon@partners.org
Laboratory URL:http://www.generatios.com/
Dana-Farber/Harvard Cancer Center URL:http://www.dfhcc.harvard.edu/member_detail.asp?memberID=8883
Brigham and Women's Hospital URL:http://www.brighamandwomens.org/surgery/research/facultypages/GordonResearch.asp

Delores J. Grant, Ph.D., 1995
Dissertation title: Expression of the Haptoglobin Gene Complex
Advisor: Nobuyo N. Maeda
Current Position: Assistant Professor, Department of Biology, North Carolina Central University, Durham, NC
E-Mail: dgrant@wpo.nccu.edu
URL: http://www.nccu.edu/artsci/biology/faculty.html#GRANT

Danny R. Gray, Ph.D., 2005
Dissertation title:  Effects of Androgen Deprivation on the Human Prostate Microenvironment
Advisor: Gary J. Smith
Current Position:  Postdoctoral Research Fellow, Molecular and Vascular Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA
Email: dgray@bidmc.harvard.edu

H
Michel G. Haddad, M.S., 1985
Thesis title:  Idiotpy and Factor VIII Inhibitors: Towards the Production of a Monoclonal Anti-Idiotypic Antibody
Advisor:  Howard M. Reisner

Perry F. Harris, M.D., D.V.M., M.S., 1959
Thesis title: Hemophilic Heterozygotes: A Reevaluation of the Concentration of Antihemophilic Factor in Their Plasma
Advisor:  Robert H. Wagner

Timothy P. Heffernan, Ph.D., 2005
Dissertation title:  Mechanisms of S Checkpoint Function in Human Cells
Advisor: William K. Kaufmann
Current Position:  Postdoctoral Research Fellow, Massachusetts General Hospital, Harvard Medical School, Boston, MA
Email:  timothy.heffernan@cbrc2.mgh.harvard.edu

Alexis T. Henry, M.S., 2001
Thesis title: Characterization of Single Nucleotide Polymorphisms (SNPs) in Protein C Inhibitor
Advisor: Frank C. Church
Current Position:  Diosynth RTP Inc., Research Triangle Park, NC
Email:  alexis.henry@diosynth-rtp.com
URL:  http://www.advancesinlifescience.com/default.asp

Susan D. Hester, Ph.D., 2003
Dissertation title: Genetic Events Involved in Formaldehyde-induced Carcinogenesis
Advisor: Douglas C. Wolf
Current Position: Research Biologist, Cancer Biology Branch, NHEERL/ECD, US Environmental Protection Agency, Research Triangle Park, NC
Email: Hester.Susan@epamail.epa.gov

Brandi Whitley Hilder, Ph.D., 2004
Dissertation title:  Plasminogen Activator Inhibitor-1 in Breast and Ovarian Cancer Invasion
Advisor: Frank C. Church
Current Position:  Clinical Research Fellow, Cato Research, Durham, NC
Email:  bhilder@cato.com
URL:  http://www.cato.com/

Jeffrey B. Hodgin, Ph.D., M.D., 2002
Dissertation title: Molecular Mechanisms of Atheroprotection by 17b-estradiol
Advisor: Nobuyo N. Maeda
Current Position: Chief Resident, Department of Pathology, Columbia University Medical Center, New York, NY
Email: jeh9026@nyp.org

Steven C. Hoffman, M.S., 1995
Thesis title: Altered Expression of the p53 Tumor Suppressor Gene Enhances the Tumorigenic Potential of Neoplastically Transformed WB-F344 Rat Liver Epithelial Cells
Advisor: Gary J. Smith
Current Position: Senior Research Associate, Transplantation Section, NIDDK Transplantation and Autoimmunity Branch, National Institute for Diabetes & Digestive & Kidney Diseases, National Institutes of Health, Bethesda, MD
E-mail: steveh@intra.niddk.nih.gov
URL: http://www.niddk.nih.gov

Kelly A. Hogan, Ph.D., 2001
Dissertation title: Fibrinogen Vlissingen/Frankfurt IV: Studies with Recombinant Fibrinogen and Gene-Targeted Mice
Advisor: Susan T. Lord
Current Position: Lecturer, Department of Biology, University of North Carolina, Chapel Hill, NC
Email: kelly_hogan@unc.edu

Julia K. Holtz, M.S., 1994
Thesis title: Defining the Functional Domains of the NaeI Restriction Endonuclease by Random Mutagenesis
Advisor: Michael D. Topal

Shelley L. Hoogstraten-Miller, D.V.M., M.S., 1992
Thesis title: Von Willebrand Factor in Plasma, Platelets, and Selected Tissues of Ferrets
Advisor: Dwight Bellinger

Joe Paul Hurt, M.D., M.S., Ph.D., 1965
Thesis title: Further Purification of Beta Alanine Precipitated Human Antihemophilic Factor (AHF) by Adsorption or Reprecipitation
Advisor:  Robert H. Wagner

Joe Paul Hurt, M.D., M.S., Ph.D., 1970
Dissertation title: Dynamics of Diffuse Introvascular Coagulation Associated With an Experimental Glioma
Advisor:  Krigman

I
Samy Samuel Iskandar, M.D., Ph.D., 1983
Dissertation title:  The Pathogenesis of Heterologous Protein-induced Glomerulonephritis: Studies in Inbred Mouse Strains
Advisor:  J. Charles Jennette
J
Jennifer E. Jahn, Ph.D., 2007
Dissertation title:  Identification of Synaptotagmin XIII as a Liver Tumor Suppressor Gene
Advisor: William B. Coleman
Current Position:  Postdoctoral Fellow, Medical University of South Carolina, Charleston, SC
Email: jahnj@musc.edu

Hitendra S. Jethwa, Ph.D., 1998
Dissertation title: Molecular Characterization of the Spontaneous Anti-Myeloperoxidase Antibody Response in SCG/Kj Mice
Advisor: J. Charles Jennette
Current Position: Scientist, Molecular and Cellular Bioassay, Biogen Inc., Cambridge, MA
E-mail: Vijay_Jethwa@biogen.com

K
William K. Kaufmann, Ph.D., 1979
Dissertation title:  Studies of the Susceptibility of Hepatocytes in Specific Cell Cycle States to Carcinogenesis by N-Methyl-N-Nitrosourea
Advisor:  David G. Kaufman
Current Position: Professor, Department of Pathology and Laboratory Medicine, UNC Lineberger Comprehensive Cancer Center, University of North carolina School of Medicine, Chapel Hill, NC
E-mail: william.kaufmann@pathology.unc.edu
URL: http://www.pathology.unc.edu/path/common/kaufmann.htm

Sheryl Kathrein, M.S., 1975
Thesis title:  A Comparison of Cryoprecipitate Yeilds by Different Methods
Advisor:  James E.T. Laningham

Theodore Hyde Kiesselbach, M.D., Ph.D.
Dissertation title: Coagulation Factor XIII: A Thrombin-labile Protein in Plasma, Platelets, and Bone Marrow Megakaryocytes
Advisor:  Robert H. Wagner

Suzanne L. Kirby, M.D., Ph.D.
Dissertation title: Bone Marrow Stromal Proteoglycans and Their Roles in Hematopoiesis
Advisor: Stuart A. Bentley
Current Position:  Assistant Professor, Department of Pathology and Laboratory Medicine, University of North Carolina School of Medicine, Chapel Hill, NC
E-mail:  slk@email.unc.edu
URL: http://cancer.med.unc.edu/serodykirbylab/

L
James Christian Lamb IV, J.D., Ph.D., 1975
Dissertation title:  1951-New Factors in the Regulation of Exocrine Pancreatic Secretion in the Rat
Advisor:  J.D. Geratz

Mary Ann Pregnall Lamb, Ph.D., 1981
Dissertation title: Immunochemical Studies on the Multimeric Structure of Factor VIII Related Antigen
Advisor:  Robert H. Wagner
Current Position:  Vice President, Regulatory Affairs, Talecris Biotherapeutics, Inc., Clayton, NC
E-mail:  maryann.lamb@talecris.com

Roy Vernon Land, M.D., M.S., 1967
Thesis title: A study of Some Effects of E. coli Endotoxin on Rabbit Blood Platelets
Advisor:  Kenneth M. Brinkhous

James V. Lange, Ph.D., 1983
Dissertation title:  Rickettsial Studies: Isolation and Quantitation of Rickettsiae in Patients With Rocky Mountain Spotted Fever and Production of Monoclonal Antibodies to Rickettsia rickettsii
Advisor:  David H. Walker

Charlotte A. Lanteri, Ph.D., 2005
Dissertation title:  Mechanisms of Uptake and Action of DB75 [2,5-bis(4-amidinophenyl)furan] in African Trypanosomes
Advisor: Richard R. Tidwell
Current Position:  Postdoctoral Research Fellow, Department of Microbiology, Walter Reed Army Hospital, Silver Spring, MD
Email:  charlotte.lanteri@pathology.unc.edu

Donald W. Lawrence, Jr., Ph.D., 1998
Dissertation title: The Regulation of Human Neutrophil Adhesion and Spreading by 3',5'-cyclic Guanosine Monophosphate
Advisor: Katherine B. Pryzwansky
Current Position: Research Associate, Department of Biochemistry and Molecular Biophysics, Washington University School of Medicine, St. Louis MO
E-mail: lawrence@biochem.wustl.edu
URL: http://biochem.wustl.edu/

Daniel L. Leonard, M.S., 1974
Thesis title:  Measurements of Chromium in Hair and Soft Tissue Using Flameless Atomic Absorption (FAA) Spectroscopy
Advisor:  Robert A. Goyer

Daniel L. Leonard, M.S., 1974
Thesis title:  Metabolic Effects of Oral NTA and Equivalent Injection Dose Administration of NTA and EDTA in the Adult Rat
Advisor:  Robert A. Goyer

E. Carwile LeRoy, M.D., M.S., 1958
Thesis title:  1933-Historical and Experimental Studies of the Spontaneous Agglutination of Mammalian Blood Platelets
Advisor:  Kenneth M. Brinkhous

Richard M. Lewis, Ph.D.
Dissertation title:  Studies on the Binding of Human Anti-Factor IX Antibodies to Factor IX Protein
Advisor:  Howard M. Reisner

Terrence D. Lewis, Ph.D., 2007
Dissertation title:  Mechanisms of Estrogen Sensitivity in the Human Endometrium
Advisor: David G. Kaufman
Current Position:  Medical Student, George Washington University School of Medicine and Health Sciences, Washington DC
Email:  tdlewis@gwu.edu

Ying Li, M.S., 1991
Thesis title: Repair of BPDE-DNA in Human Fibroblasts
Advisor: William K. Kaufmann

Richard John Russell Lombardy, M.S., 1987
Thesis title:  Computer-assisted Molecular Modeling Studies of Potent Amidine Inhibitors Bound to the Active Site of Trypsin
Advisor:  Richard R. Tidwell

Kenneth M. Lovette, M.S., 1975
Thesis title:  The Subcellular Distribution and Partial Characteerization of Cholinesterase Activities in Canin Platelets
Advisor:  Hanson Chuang

Tara N. Lyons-Darden, Ph.D., 2000
Dissertation title: The Role of DNA Instability in Triplet Repeat Expansion During in vitro DNA Replication
Advisor: Michael D. Topal
Current Position: Postdoctoral Fellow, Cellular and Molecular Toxicology Branch, Neurotoxicology Division/NHEERL/ORD, U.S. Environmental Protection Agency, Research Triangle Park, NC
Email: lyons-darden.tara@epa.gov

M
B. Alston Macon, Jr., M.S., 1975
Thesis title: Calcium Induced Conformational Changes in the Amino Acid Terminal End of Prothrombin
Advisor:  Koehler

Daniel S. Marsman, Ph.D., 1991
Dissertation title: Peroxisome Proliferator Hepatocarcinogenesis in Rats: The Role of Cell Replication in Tumor Development
Advisor: James A. Popp

Reginald Gladstone Mason, M.D., M.S., 1964
Thesis title: 1933-Studies on the Platelet Agglutinating Activity of Recalcified Normal and Pathologic Human Plasmas
Advisor:  Kenneth M. Brinkhous

Marc J. Mass, Ph.D., 1980
Dissertation title:  Species Differences in the Activation of a Carcinogen in Respiratory Epithelium: A Possible Explanation for the Unequal Susceptibilities of Tracheal Epithelium of Rats and Hamsters to Carcinogenesis by Benzo(a)pyrene
Advisor:  David G. Kaufman

Dean M. McCord, Ph.D., 1992
Dissertation title: Structure-Function Relationships in Human Coagulation Factor IX
Advisor: Harold R. Roberts
Current Position: Attorney at Law, Smith, Anderson, Blount, Dorsett, Mitchell & Jernigan, L.L.P., Raleigh NC
E-mail: dmccord@smithlaw.com

Richard D. McFarland, Ph.D., 1990
Dissertation title: Mutagenesis in the Lambda Immunoglobulin Gene in a Human Lymphoblastoid Cell Strain
Advisor: Gary J. Smith

William Dumas McLester, M.D., Ph.D., 1967
Dissertation title: Studies on Circulating Anticoagulants in Classical Hemophilia and Christmas Disease
Advisor:  Robert H. Wagner

Debra K. McMahon, Ph.D., 1993
Dissertation title: Characterization of a Two Motif Isoform of the Dihydropyridine Receptor in Skeletal Muscle
Advisor: Nadia N. Malouf
Current Position:  Vice President, CardioConcepts, Inc., Charlottesville, VA
E-mail:  dmcmahon@cstone.net
URL:  www.cardioconcepts.com

Tessie Brown McNeely, Ph.D., 1984
Dissertation title:  Heparin: A Theory on Its In Vitro Anticoagulant Mechanism of Action
Advisor:  Michael J. Griffith

Jennifer Wemhoff Mitchell, Ph.D., 2001
Dissertation title: The Structure, Function, and Physiological Role of Heparin Cofactor II
Advisor: Frank C. Church
Current Position:  Postdoctoral Fellow, Department of Cell Biology, The Scripps Research Institute, La Jolla, CA
Email:  jwmitch@scripps.edu
URL: http://www.scripps.edu/cb/miles/

Douglas Edward Mooreside, M.D., M.S., 1971
Thesis title: The Effects of Adenine on the Clotting Factors in Fresh Blood, Stored Blood, and Stored Fresh Frozen Plasma
Advisor:  James E.T. Laningham

N
Mohammad A. Nadjem, M.D., M.S., 1969
Thesis title:  A Study of the Anatomical Pathology of Liver Fluke Infestation (Opisthorchis viverrini) in Thai
Advisor:  Sylvanus W. Nye

Laura L. (Neese) Glasscock, Ph.D., 1997
Dissertation title: Protein C Inhibitor: Structure-Activity Relationships and Pathobiological Aspects
Advisor: Frank C. Church
Current Position: Assistant Professor, Department of Biology, Winthrop University, Rock Hill, SC, and Assistant Director of Urology Research, Cannon Research Center, Carolinas Hospital, Charlotte, NC
E-mail: glasscockl@winthrop.edu
URL: http://www.winthrop.edu/biology/facstaff/glasscock.htm

Suzanne T. Newberry, M.S., 2002
Thesis title: Methylation-dependent Epigenetic Silencing of BRCA1 in Sporadic Breast Cancer
Advisor: William B. Coleman
Current Position: Math and Science Program Coordinator, Information Technology and Sciences Division, Camplain College, Burlington, VT
Email:  sunewberry@burlingtontelecom.net

Waykin Nopanitaya, Ph.D., 1971
Dissertation title:  Effects of the Pungent Principle of Hot Red Pepper (Capsaicin) in Combination With Diets of Varying Protein Content on the Duodenal Absorptive Cells and the Growth of the Rat
Advisor:  Sylvanus W. Nye

O
Paula M. Oliver, Ph.D., 1997
Dissertation title: Targeted Gene Titration of the Natriuretic Peptide Receptor A to Study Its Role in Essential Hypertension
Advisor: Nobuyo N. Maeda
Current Position: Postdoctoral Fellow, University of Colorado Health Sciences Center, Bolder, CO
E-mail: oliver@njc.org

Michael S. Owens, Ph.D., 1980
Dissertation title:  Marijuana Use Among Drivers in Fatal Single-vehicle Accidents
Advisor:  Arthur McBay

P
Joan P. Packenham, Ph.D., 1992
Dissertation title: Effect of Estradiol on Von Willebrand Factor Expression in Cultured Endothelial Cells
Advisor: Cora-Jean S. Edgell
Current Position: Scientific Program Administrator, Chemical Exposures and Molecular Biology Branch, Division of Extramural Research and Training, National Institute of Environmental Health Sciences, Research Triangle Park, NC
E-mail: packenhm@niehs.nih.gov

Diane Palmieri, Ph.D., 2000
Dissertation title: Serpins in Cancer
Advisor: Frank C. Church
Current Position: Cancer Research Training Award Fellow, Women's Cancer Section, National Cancer Institute, NIH, Bethesda, MD
Email: palmierd@mail.nih.gov

Arti C. Patel, Ph.D., 2000
Dissertation title: Analysis of Candidate Suseceptability Genes and the Role of DNA Methylation in Mouse Lung Carcinogenesis
Advisors: J. Carl Barrett and Theodora R. Devereux
Current Position: Postdoctoral Fellow, Laboratory of Tumor Immunology and Biology, National Cancer Institute, NIH, Bethesda, MD
Email:patelar@mail.nih.gov

Richard S. Paules, Ph.D., 1984
Dissertation title:  An Investigation of the Effects of Exposure to a Chemical Carcinogen on DNA Replication in Mammalian Cells Utilizing Quantitative EM Visualization of Antibodies Bound to Carcinogen-DNA
Advisor:  David G. Kaufman
Current Position: Director of Toxicologic Gene Expression Studies, Toxicogenomics Facilitator in Molecular Toxicology, National Center for Toxicogenomics, National Toxicology Program, Laboratory of Environmental Carcinogenesis, Growth Control and Cancer Group, National Institute of Environmental Health Sciences, Research Triangle Park, NC
E-mail: paules@niehs.nih.gov
URL: http://www.niehs.nih.gov/nct/grocontrl.htm

William F. Pendergraft III, Ph.D.
Dissertation title: In Depth Analysis of the Myeloid Protease, Proteinase 3, as an Autoantigen and a Mediator of Vascular Injury
Advisor: Ronald J. Falk
Current Position: Postdoctoral Fellow, Department of Pathology and Laboratory Medicine, University of North Carolina School of Medicine, Chapel Hill, NC
Email: will_pendergraft@med.unc.edu

Arlene S. Pereira, Ph.D., 2000
Dissertation title:A Study of Antiretroviral Drug Penetration into the Male Genital Tract Using High Performance Liquid Chromatography and Tandem Mass Spectrometry
Advisor: Richard R. Tidwell
Current Position: Research Assistant Professor, Division of Drug Delivery and Disposition, University of North Carolina School of Pharmacy, Chapel Hill, NC
Email:  argoyle@email.unc.edu

Jonathan M. Phillips, Ph.D., 1998
Dissertation title: The Association of Specific DNA Sequences with the Nuclear Matrix During G0 and S Phases of the Cell Cycle
Advisor: David G. Kaufman
Current Position: Lead Molecular Pathologist, Mitretek Systems, Falls Church, VA
E-mail: jonathan.phillips@mitretek.org
URL: http://www.mitretek.org/

Karen K. Phillips, Ph.D., 1997
Dissertation title: Identifying Suppressor Genes for Breast Cancer and Wilms’ Tumor
Advisor: Bernard E. Weissman
Current Position:  Postdoctoral Fellow, Department of Pediatrics, University of North Carolina School of Medicine, Chapel Hill, NC

Kelly L. Price, M.S., 2000
Dissertation title: Genetic Instability in Cervical Carcinogenesis
Advisor: William K. Kaufmann
Current Position: Research Assistant, Research and Development, Caliper Technologies, Mountain View CA 
E-mail: kelly.price@calipertech.com

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Richard James Rahija, Ph.D., 1989
Dissertation title:  Factors Influencing the Initiation by Anti(+)benzo(a)pyrenediol-expoxide of Hepatocarcinogesis in the Male F344 Rat
Advisor:  David G. Kaufman

Marjorie S. Read, Ph.D., 1983
Dissertation title:  Venom Coagglutinin (VCA).  The Platelet Aggregating Principle of Bothrops Venoms: Von Willibrand Factor-dependent Platelet Aggregation
Advisor:  Kenneth M. Brinkhous

Robert L. Reddick, M.D., M.S., 1971
Thesis title:  Thrombocytopenia of Hibernation: With Special Reference to the Role of the Spleen.
Advisor:  Penick
Current Position:  Frank M. Townsend Professor of Pathology and Chair, Department of Pathology, The University of Texas Health Science Center, San Antonio, TX
Email:  reddick@uthscsa.edu
URL:  http://pathology.uthscsa.edu/faculty/reddick.htm

Sharon Ricketts (Betz), Ph.D., 2007
Dissertation title: Identification and Characterization of Candidate Liver Tumor Suppressor Genes from Human Chromosome 11p11.2-p12
Advisor: William B. Coleman
Current Position: Assistant Professor, Assistant Director of the Cytogenetics and Molecular Diagnostics Laboratories, Department of Pathology, University of Michigan Medical School, Ann Arbor, MI
Email: sbetz@med.umich.edu

Michelle A. Rider, M.S., 2000
Thesis title: Suppression of Tumorigenicity in Rat Liver Tumor Cells by Human Chromosome 13: Evidence Against the Involvement of pRb
Advisor: William B. Coleman
Current Position: Veterinary Student, University of Minnesota, Minneapolis, MN
Email: ride0018@umn.edu

Thomas H. Rude, M.S., 1991
Thesis  title: Cloning and Sequencing of the Cryptococcus neoformans NAD-dependent Mannitol Dehydrogenase Gene
Advisor: Christine C. Dykstra

Julie L. Ryan, Ph.D., 2005
Dissertation title:  Prevalence of Epstein-Barr Virus in Gastric Mucosa and Influences on Selected Gene Expression in Gastric Carcinoma
Advisor: Margaret L. Gulley
Current Position:  Research Assistant Professor, Departments of Dermatology and Radiation Oncology, University of Rochester Cancer Center, Rochester, NY
Email:  julie_ryan@urmc.rochester.edu

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Hussian Ismail Saba, M.D., Ph.D.
Dissertation title: Effects of Polymorphonuclear Leukocytes on Blood Coagulation and Fibrinolysis
Advisor:  Harold R. Roberts

Fernando A. Santos, M.D., Ph.D., 1978
Dissertation title: Purification and Characterization of Bovine Platelet Aggregating Factor (PAF): I: Purification of PAF. II: Immunological Characterization of PAF.
Advisor:  Robert H. Wagner

Kimberly Weiss Schuenke, Ph.D., 1993
Dissertation title: Analysis of a Novel Protein Antigen Gene of Rickettsia Conorii
Advisor: David H. Walker
Current Position:  Associate Director, Center for Biodefense and Emerging Infectious Diseases, The University of Texas Medical Branch, Galveston, TX
E-mail:  kischuen@utmb.edu

Mark de Serres, M.S., 1987
Thesis title: A Monoclonal Antibody Whose Binding is Inhibited by Divalent Cations
Advisor:  Howard M. Reisner

David Edward Sharp, M.D., Ph.D., 1975
Dissertation title: 1945-Morphologic Studies on Blood Platelet Response to Adenosine Diphosphate and Its Modification InVivo and In Vitro
Advisor:  Mason

Rebecca A. Shirk, Ph.D., 1994
Dissertation title: Structure-Function Studies of Heparin Binding Serpins
Advisor: Frank C. Church
Current Position: Research Associate, Temple University, Philadelphia, PA

Brian G. Short, Ph.D., 1988
Dissertation title:  Effects of Unleaded Gasoline on Renal Tubular Cell Kinetics and Tumor Promotion in Rats
Advisor: James A. Swenberg

Otis Speight, M.S., 1985
Thesis title:  Pathogenesis of Murine Infection Wtih Parainfluenza Virus in Mice: A Natural Paramyxovirus-Host Relationship
Advisor:  David H. Walker

Lisa Marie Sturk, Ph.D., 2005
Dissertation title:  Comparative Pharmacokinetics of DB289 and DB844: Investigating Improved Prodrug Efficacy Against Mouse Models of Sleeping Sickness 
Advisor: Richard R. Tidwell
Current Position:  Scientist, In Vivo Resources, Shire Pharmaceuticals, Cambridge, MA
Email:  lmsturk@tktx.com
URL:  www.shire.com

Liisa Sundberg Smith, Ph.D., 2007
Dissertation title:  A Role for Focal Adhesion Kinase in Vascular Smooth Muscle Cell Proliferation, Migration, and Differentiation
Advisor: Joan M. Taylor
Current Position:  Postdoctoral Research Fellow, Department of Pathology and Laboratory Medicine, University of North Carolina School of Medicine, Chapel Hill, NC
Email:  liisa.smith@pathology.unc.edu

Lara K. Surles, M.S., 1995
Thesis title: The Paradoxical Effects of Lovastatin, an HMGCoA Reductase Inhibitor, on Apolipoprotein E Deficient Mice
Advisor: Nobuyo N. Maeda

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Larry Paul Thornburg, L.P., D.V.M., M.S., 1974
Thesis title: Direct Enzyme Cytochemical Investigation of the Trigeminal Ganglion of C57BL/6J-dtj Mice and Their Littermates With an Hereditary Sensory Neuropathy (Dystonia Musculorum)
Advisor:  Stowe/Hanker

Vincent R. Torti, Ph.D., 1999
Dissertation title: Cellular Aging in Endometrial Stromal Cells Promotes the Growth of Immortalized and Carcinoma-derived Endometrial Epithelial Cells via Paracrine Interactions: The Role of Interleukin-1a and Interleukin-1b
Advisor: David G. Kaufman
Current Position:  Scientist, Amgen, Thousand Oaks, CA
E-mail: vtorti@amgen.com
URL: http://www.amgen.com/

Yau-Sheng Tsai, Ph.D., 2005
Dissertation title:  Peroxisome Proliferator-Activated Receptor Gamma in the Metabolic Syndrome
Advisor: Nobuyo Maeda
Current Position:  Assistant Professor, National Cheng Kung University, Tainan, Taiwan
Email:  yaustsai@mail.ncku.edu.tw

Jo Ann Tyndall, M.S., 1989
Thesis title:  Azurophil and Specific Granule Exocytosis by N-formyl-methionyl-leucyl-phenylalanine-stimulated Human Neutrophils
Advisor:  Katherine B. Pryzwansky

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Gerald William Upton, D.D.S., M.S., Ph.D., 1981
Dissertation title:  Platelet Inhibition and Thrombosis in the Pathogenesis of Bacterial Diseases
Advisor:  Frederic G. Dalldorf
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Romas Agu Vaitkus, M.S., 1988
Thesis title:  Transformation of Human Endometrial Stromal Cells With a Temperature-sensitive, Origin-minus, SV40 Recombinant Plasmid
Advisor: David G. Kaufman

Christine Norma Vogel, Ph.D., 1978
Dissertation title:  In Vivo and In Vitro Biology of Antithrombin III and Thrombin
Advisor:  Roger Lundblad

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Yung Sheng Eric Wang, Ph.D., 1985
Dissertation title:  Plasma Free Fatty Acids: Development and Clinical Application of a New Analytical Method
Advisor:  William W. McLendon

William Phillip Webster, D.D.S., M.S., 1968
Thesis title: Studies of In Vivo and Ex Vivo Release of Factor VIII From Organs and Tissues
Advisor:  Penick

Herbert C. Whinna, M.D., Ph.D., 1992
Dissertation title: Structure Function Studies on Heparin Cofactor II
Advisor: Frank C. Church
Current Position: Clinical Associate Professor; Director, Clinical Coagulation and Laboratory Information Services, Department of Pathology and Laboratory Medicine, University of North Carolina, Chapel Hill, NC
E-mail: herbert.whinna@pathology.unc.edu
URL: www.pathology.unc.edu

Gilbert C. White, M.D., M.S., 1975
Thesis title: The Effect of Various Anticoagulants on the Adhesiveness of Blood Platelets and Studies on the Mechanism of Platelet Adhesion.
Advisor:  Kenneth M. Brinkhous
Current Position:  Professor of Pharmacology and Medicine, Department of Pharmacology, University of North Carolina School of Medicine, Chapel Hill, NC
Email:  gcwhite@med.unc.edu
URL:  http://www.med.unc.edu/wrkunits/2depts/pharm/white.htm

Brandi Whitley (Hilder), Ph.D., 2004
Dissertation title:  Plasminogen Activator Inhibitor-1 in Breast and Ovarian Cancer Invasion
Advisor: Frank C. Church
Current Position:  Clinical Research Fellow, Cato Research, Durham, NC
Email:  bhilder@cato.com
URL:  http://www.cato.com/

Dorothy H. Wood, Ph.D., 2001
Dissertation title: The Role of Imidazoline Receptors in 1,5-Bis(4-Amidinophenoxy) Pentane (Pentamidine) Toxicity
Advisor: Richard R. Tidwell
Current Position: Visiting Assistant Professor, Department of Biology, North Carolina Central University, Durham, NC
Email: dwood@wpo.nccu.edu
URL: http://www.nccu.edu/artsci/biology/biology.html

Todd A. Wyatt, Ph.D., 1992
Dissertation title: Neutrophil cGMP-Dependent Protein Kinase: Its Identification and Response to Formyl-Peptide and Calcium Ionophore
Advisor: Katherine B. Pryzwansky
Current Position: Associate Professor of Medicine, Pulmonary and Critical Care Medicine, Department of Internal Medicine, University of Nebraska Medical Center, Omaha, NE
E-mail: twyatt@unmc.edu
URL:  http://app1.unmc.edu/intmed/department/bio.cfm?MyID=44&section=Pulmonary%20%26%20Critical%20Care

George Peter Wysocki, D.D.S., Ph.D., 1971
Dissertation title: Synovial Membrane Changes in Hemophilic Arthopathy: A Light, Transmission and Scanning Electron Microscope Study
Advisor:  Kenneth M. Brinkhous

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Nazumi Alice S. Yamada, Ph.D., 2002
Dissertation title:Microsatellite Instability in the Absence of Mismatch Repair Defects
Advisor: Rosann A. Farber
Current Position: Postdoctoral Research Staff Member, DNA Repair Team, Biology and Biotechnology Research Program, Lawrence Livermore National Laboratory, Livermore, CA
Email:  yamada3@llnl.gov
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Sunny H. Zhang, Ph.D., 1994
Dissertation title: An Animal Model of Atherosclerosis: The Apolipoprotein E Deficient Mice
Advisor: Nobuyo N. Maeda
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