Rupninder Sandhu
M.B.B.S., Medicine
Government Medical College
Amritsar, India
I am originally from Nawanshahar, Punjab, a small town located in northwest of India. I received my degree in Medicine, M.B.B.S from India and was subsequently trained as ENT surgeon.  I started the Molecular and Cellular Pathology Graduate program at UNC in August 2006.  During my first year, I did three research rotations.  My first rotation project was in the laboratory of Dr. Alisa Wolberg.  In her lab, I worked on understanding the pathogenesis of Antiphospholipid Syndrome especially in relation to interactions between Beta-2 Glycoprotein1 and Annexin A2.  My second rotation was in the laboratory of Dr. William Coleman, where my rotation project focused on increasing the efficacy of chemotherapeutics using demethylating agents in hypermethylator breast tumor cells.  I also rotated in the laboratory of Dr. Young Whang, where my rotation project focused on the regulation of androgen receptor activity in progression of prostate cancer in relation to the role of cytoplasmic signaling pathways.  I joined the lab of Dr. William Coleman in May 2007 where I am working on breast cancer research project and looking into different ways to sensitize breast tumor cells to chemotherapeutics along with the epigenetic mechanisms playing a role in the process.

      In my spare time, I like to spend time with my husband and our son, Avneet, and to watch movies.

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