| Abstracts
and Presentations from 2007
Beaulieu, L.M., Gramling, M., and Church, F.C. (2007) Activated protein C has both extracellular and intracellular effects on breast cancer and endothelial cell migration. FASEB J. 21:A386. Best, D.H. and Coleman, W.B. (2007) Destruction of bile ducts by 4,4’-diaminodiphenylmethane does not block the small hepatocyte-like progenitor cell response in retrorsine-exposed rats. FASEB J. 21:A70. Best, D.H. and Coleman, W.B. (2007) Liver regeneration after carbon tetrachloride injury in retrorsine-exposed rats. FASEB J. 21:A188. Canos, D.A., Avery, C.L., Franceschini, N., Maeda, N., Muallem, H., Grove, M.L., Boerwinkle, E., and North, K.E. (2007) The consistent effect of low density lipoprotein-receptor mutations on incident coronary heart disease across strata of Apolipoprotein E alleles: the ARIC Study. American Heart Association Scientific Sessions Conference. Franceschini, N., Muallem, H., Wojczynski, M.K., Rose, K.M., Boerwinkle, E., Volcik, XK.A., Li, X., Wilhelmsen, K.C., Maeda, N., and North, K.E. (2007) The effect of LDL receptor diplotypes and its interaction with Apolipoprotein E polymorphisms on carotid artery wall thickness: The Atherosclerosis Risk In Communities Study. Medlin, M. and Mack, C.P. (2007) Molecular regulation of RhoA activity and its role in smooth muscle cell differentiation. 2007 Southeast Regional Meeting of The Society for Developmental Biology, Chapel Hill, NC. Polisecki, E., Muallem, H., Maeda, N., Trompet, S., Jukema, W., McMahon, A., Robertson, M., Ford, I., Blauw, G., Murphy, M., Shepherd, J., and Schaefer, E. (2007) Variation at the PCSK9 and LDLR locus, LDL Levels, and heart disease in PROSPER. Arteriosclerosis, Thrombosis, and Vascular Biology. Risher, J.D. and Coleman, W.B. (2007) Aberrant DNA methyltransferase 3b activity accounts for the hypermethylator phenotype in human breast cancer cell lines. FASEB J. 21:A755. Risher, J.D., Rivenbark, A.G., and Coleman, W.B. (2007) Methylation status of CEACAM6 predicts hypermethylator phenotype among human breast cancer cell lines. FASEB J. 21:A756. White, K.K., Belloni, D.R., Booker, J., Silverman, L.M., Tsongalis, G.J., Highsmith, W.E., and Coleman, W.B. (2007) +ACA BRCA1 promoter polymorphism occurs frequently in the general population. FASEB J. 21:A753. White, K.K., Wilson, C., Booker, J., Silverman, L.M., Bowser, R., and Coleman, W.B. (2007) Expression of BRCA1 and FAC1 in human primary breast cancer. FASEB J. 21:A754. |
| Abstracts
and Presentations from 2006
Altenburg, M., Johnson, L., and Maeda, N. (2006) LDLr dependent sinusoidal localization of ApoE3, but not ApoE2. Gordon Conference on Lipoprotein Metabolism. Best, D.H. and Coleman, W.B. (2006) Treatment with 2AAF blocks the SHPC regenerative response in retrorsine-exposed rats. FASEB J. 20:A1379. DelBove, J.N., Stroebeck, M.W., Knudson, E.S., Wang, W., Chen, J., Archer, T.K., and Weissman, B.E. (2006) Characterization of the loss of BAF155 of the SWI/SNF chromatin remodeling complex in human cancer cell lines. Proceed. Am. Asso. Cancer Res. 47:99a. Jahn, J.E. and Coleman, W.B. (2006) A potential role for synaptotagmin XIII (SYT13) in epithelial-mesenchymal transition. FASEB J. 20:A202. Jahn, J.E. and Coleman, W.B. (2006) Phenotypic normalization of GN6TF rat liver tumor cells results from WT1 expression following transfection of human SYT13-containing BACs. FASEB J. 20:A1091. Karaca, M. and Weissman, B.E. (2006) Induction of dominant-negative BRG1 abolishes expression of CD44 protein via post-transcriptional mechanism in mouse NIH/3T3 cells. Proceed. Am. Asso. Cancer Res. 47:5063a. Mangiante, L.E., Smith, L.S., Beggs, H., Reichardt, L.F., Mack, C.P., and Taylor, J.M. (2006) Impaired cell polarization in FAK-depleted smooth muscle cells. NAVBO Development Vascular Biology Workshop, Monterey, CA. Risher, J.D., Rivenbark, A.G., and Coleman, W.B. (2006) Investigation of the CpG island methylator phenotype reveals two methylation classes among breast cancer cell lines. FASEB J. 20:A220. Rivenbark, A.G., Buckley, B.K., White, K.K., Coleman, W.B., and Thomas, D.B. (2006) Molecular analysis of bilateral mature cystic ovarian teratoma. Modern Pathology 19:194A. Staus, D. and Mack, C.P. (2006) Regulation of smooth muscle differentiation by the diaphanous-related formins. NAVBO Development Vascular Biology Workshop, Monterey, CA. White, K.K., Wilson, C., Belloni, D.R., Booker, J., Silverman, L.M., Gardner, K.L., Tsongalis, G.J., Bowser, R., and Coleman, W.B. (2006) A novel +ACA BRCA1 promoter polymorphism creates a binding site for the FAC1 transcriptional repressor. FASEB J. 20:A1324. |
| Abstracts
and Presentations from 2005
Altenburg, M., Johnson, L., and Maeda, N. (2005) LDL receptor expression in macrophage affects atherogenesis in an ApoE isoform dependent manner . Gordon Conference on Atherosclerosis. Beaulieu, L.M. and Church, F.C. (2005) Role of the Protein C system in endothelial and breast cancer cell migration. XXth Congress of the International Society of Thrombosis and Hemostasis, Sydney, Australia. Best, D.H., Butz, G.M., and Coleman, W.B. (2005) Cytokine-dependence of small hepatocyte-like progenitor cell activation in rats with retrorsine-induced hepatocellular injury. FASEB J. 19:A477. Campbell, R.A., Fischer, T.H., and Wolberg, A.S. (2005) Reconstituted, lyophilized platelets generate thrombin in the presence of recombinant Factor VIIa. Blood 106:4057a. Charboneau, A.L., Chai, J., Betz, B., and Weissman, B.E. (2005) P-Akt/SNF5 signaling interactions in rhabdoid tumors. Proceed. Am. Asso. Cancer Res. 46:4544a. Chastain, P.D., Heffernan, T.P., Kaufmann, W.K., Kaufman, D.G., and Cordeiro-Stone, M. (2005) Visualization of replication dynamics after UVC-induced DNA damage in HeLa cells. Cold Spring Harbor Symposium on Eukaryotic DNA Replication, Cold Spring Harbor, MA. DelBove, J.N., Knudson, E.S., Strobeck, M.W., and Weissman, B.E. (2005) Characterization of the loss of BAF155 of the SWI/SNF chromatin remodeling complex in human cancer cell lines. Proceed. Am. Asso. Cancer Res. 46:1956a. DiMichele, L., Doherty, J.T., Rojas, M., Mack, C.P., and Taylor, J.M. (2005) A role for focal adhesion kinase in cardiac hypertrophy. Keystone Symposium on Cardiovascular Development and Disease, Keystone, CO. Fortenberry, Y., Rau, J., Cranford, L., Myles, T., Leung L., and Church, F. (2005) Molecular characterization of plasminogen activator inhibitor (PAI-1)/thrombin inhibition in the absence and presence of heparin and vitronectin (VN). XXth Congress of the International Society on Thrombosis and Haemostasis, Sydney, Australia. Gregory, C.W., Whang, Y.E., McCall, W., Fei, X., Liu, Y., Ponguta, L.A., French, F., Wilson, E., and Earp, H.S. (2005) Involvement of HER-2 and HER-3 receptor tyrosine kinases in androgen receptor function and recurrent prostate cancer growth. Proceed. Am. Asso. Cancer Res. 46:3200a. Hinson, J.S., Medlin, M.D., and Mack, C.P. (2005) The LIM-only protein, FHL2, interacts with serum response factor to inhibit RhoA and MRTF-A-dependent transactivation of SMC gene expression. National Meeting of the North American Vascular Biology Organization, Chicago, IL. Huss, W.J., Gray, D.R., Greenberg, N.M., Mohler, J.L., and Smith, G.J. (2005) Breast cancer resistance protein-mediated efflux of androgen in putative benign and malignant prostate stem cells. Proceed. Am. Asso. Cancer Res. 46:2051a. Jahn, J.E., Rivenbark, A.G., and Coleman, W.B. (2005) Gene expression profiling after RNAi-mediated silencing of SYT13. FASEB J. 19:A1046. Gray, D.R., Huss, W.J., Buckley, B.K., Werdin, E.S., and Smith, G.J. (2005) Androgen ablation induced vascular labilization in the human prostate is associated with enhanced vascular permeability and enhanced coagulative state. Proceed. Am. Assoc. Cancer Res. 46:1153a. Lewis, T.D., Barbier, C.S., and Kaufman, D.G. (2005) The roles of estrogen receptors alpha and beta in estrogen signalling. American Association for Cancer Research Edward A. Smuckler Memorial Workshop on Cancer Pathobiology, Keystone, CO. Merricks, E.P., Ezban, M., Persson, E., Raymer, R.A., Dillow, A., McCorquodale, S., and Nichols, T.C. (2005) Modified whole blood clotting time assay detects recombinant human FVIIa and rFVIIa analog NN1731 in canine hemophilia A blood in a dose-dependent fashion. J. Thrombosis Haemostasis 3:1362a. Rau, J., Thomas, D., Kiss, L., Zieske, A., Strong, J., and Church, F. (2005) Localization of heparin cofactor II in atherosclerotic lesions. The Fourth International Symposium on Serpin Structure, Function and Biology, Cairns, Australia. Rau, J. and Church, F. (2005) Site-directed mutagenesis of the alpha-1 protease inhibitor D-helix to that of heparin cofactor II confers heparin specific properties. XXth Congress of the International Society on Thrombosis and Haemostasis, Sydney, Australia. White, K.K., Belloni, D.R., Booker, J., Silverman, L.M., Tsongalis, G.J., and Coleman, W.B. (2005) Identification of a novel +ACA polymorphism in the BRCA1 promoter of hereditary breast cancer patients. FASEB J. 19:A1509-A510. |
| Abstracts
and Presentations from 2004
Beaulieu, L.M., Elkahloun, A., Whitley, B.R., Palmieri, D., and Church, F.C. (2004) Protein C inhibitor regulates inflammatory and apoptotic genes in MDA-MB-435 cells. FASEB J. 18:A1195. Beaulieu, L.M., Elkahloun, A., Whitley, B.R., Palmieri, D., and Church, F.C. (2004) Plasminogen activator inhibitor-1 and protein C inhibitor regulate inflammatory and apoptotic genes in MDA-MB-435 cells. Gordon Research Conference on Plasminogen Activation and Extracellular Proteolysis, Ventura, CA. Best, D.H., Coleman, W.B., Livasy, C.A., Moller, K., and Thomas, D.B. (2004) Molecular analysis of an immature ovarian teratoma with gliomatosis peritonei and recurrence suggests genetic independence of multiple tumors. Modern Pathology 17:191A. Best, D.H., Coleman, W.B., Moller, K., and Thomas, D.B. (2004) Genetic evidence for independence of multiple tumors in immature ovarian teratoma with gliomatosis peritonei and recurrence. FASEB J.18:A570. Bushman, J., Ciavatta, D., Smithies, O., and Kirby, S. (2004) Transgene-induced enhancement of hemato-vascular differentiation from murine embryonic stem cells. FASEB J. 18:A181. Chai, J., Lu, X., Godfrey, V., Van Dyke, T., Roberts, C.W., and Weissman, B.E. (2004) The inhibition of Rb family members will accelerate the rhabdoid tumor growth and induce the Schwannoma-like tumor growth in spinal cord. Proceed. Am. Asso. Cancer Res. 45:5086a. DelBove, J.N., Godfrey, V., Van Dyke, T.V., Roberts, C., and Weissman, B.E. (2004) Combined haploinsufficiency of tumor suppressors p53 and SNF5 of the SWI/SNF chromatin remodeling complex lead to decreased tumor latency and increased tumor penetrance in the mouse. Procced. Am. Asso. Cancer Res. 45:5559a. DiMichele, L., Doherty, J.T., Rojas, M., Mack, C.P., and Taylor, J.M. (2004) A role for focal adhesion kinase in cardiac hypertrophy. Keystone Symposium on Cardiovascular Development and Disease, Keystone, CO. Gray, D.R., Huss, W.J., Yau, J.M., Werdin, E.S., and Smith, G.J. (2004) Human prostate vascular dynamics following castration: A study of primary human prostate xenografts. Proc. Am. Assoc. Cancer Res. 45:2382a. Gray, D.R., Huss, W.J., Yau, J.M., Buckley, B.K., Werdin, E.S., and Smith, G.J. (2004) Androgen recepor expressing human prostate endothelial cells can be directly affected by castration and participate synergistically during vascular rebound. Soc. Basic Urologic Res., Savannah, GA. Heffernan, T.P., Unsal-Kacmaz, K., Heinloth, A.N., Paules, R.S., Sancar, A., Cordeiro-Stone, M, and Kaufmann, W.K. (2004) The ATR-dependnet UVC-induced intra-S checkpoint inhibits replicon initiation without Cdc25A degradation: Dbf4 as a potential target of Chk1. The Cell Cycle, Cold Spring Harbor Laboratories, Cold Spring Harbor, NY. Heffernan, T.P., Unsal-Kacmaz, K., Heinloth, A.N., Paules, R.S., Sancar, A., Cordeiro-Stone, M, and Kaufmann, W.K. (2004) Multiple mechanisms inhibit replicon initiation after DNA damage. Replication and Genome Integrity, Salk Institute, La Jolla, CA. Heffernan, T.P., Unsal-Kacmaz, K., Heinloth, A.N., Paules, R.S., Sancar, A., Cordeiro-Stone, M, and Kaufmann, W.K. (2004) Multiple mechanisms inhibit replicon initiation after DNA damage. Annual Meeting of the Environmental Mutagen Society, Pittsburgh, PA. Hinson, J.S., Lockman, K., Medlin, M.D., Morris, D., Taylor, J.M., and Mack, C.P. (2004) RhoA-dependent nuclear translocation of myocardin related transcription factor A is important for SMC-specific transcription. International Vascular Biology Symposium 2004, Toronto, Canada. Hinson, J.S., Lockman, K., Medlin, M.D., Taylor, J.M., and Mack, C.P. (2004) Spingosine-1-phosphate stimulates differentiation and proliferation of smooth muscle cells. Developmental Vascular Biology Workshop, Pacific Grove, CA. Huss, W.J., Gray, D.R., Durham, L.E., Harris, C.M., Greenberg, N.M., Gregory, C.W., and Smith, G.J. (2004) Tumor associated neuroendocrine cell differentiation in the CWR22 and human prostate primary xenograft models and TRAMP model following androgen deprivation. Proc. Am. Assoc. Cancer Res. 45:4063a. Huss, W.J., Tavakoli, K., Gray, D.R., Greenberg, N., and Smith, G.J. (2004) Poorly differentiated NE-like carcinoma in TRAMP as a model of human recurrent prostate cancer. Soc. Basic Urologic Res., Savannah, GA. Jahn, J.E. and Coleman, W.B. (2004) Reexpression of a tumor cell phenotype in microcell hybrid cells after RNAi-mediated silencing of SYT13. FASEB J. 18:A935. King, N.M., Nikolaishvili-Feinberg, N., Bryant, M.F., Luche, D.D., Heffernan, T.P., Simpson, D.A., Hanaoka, F., Kaufmann, W.K., and Cordeiro-Stone, M. (2004) Overexpression of DNA polymerase eta in cultured human fibroblasts. ASM Conference on DNA Repair and Mutagenesis: From Molecular Structure to Biological Consequences, Southampton, Bermuda. Lockman, K., Hinson, J.S., Medlin, M.D., Taylor, J.M., and Mack, C.P. (2004) Sphingosine-1-phosphate stimulates differentiation and proliferation of vascular smooth muscle cells. North American Vascular Biology Organization 2004, Monterrey, CA. Ponguta, L.A., Bill, H.M., Fei, X., Chen, Y., and Gregory, C.W. (2004) Repression of androgen receptor function and cellular proliferation in the CWR-R1 recurrent prostate cancer cell line with dominant negatives and RNA interference. FASEB J. 18:A935. Ryan, J.L., Morgan, D., Shen, Y.-J., Thorne, L.B., Elmore, S.H., and Gulley, M.L. (2004) Epstein-Barr virus latently infects gastric cancer and gastritis lesions. FASEB J. 18:A571. Ryan, J.L., Morgan, D., Shen, Y.-J., Thorne, L.B., Elmore, S.H., and Gulley, M.L. (2004) Epstein-Barr virus latently infects gastric cancer and gastritis lesions. The 11th Biennial Conference of the International Association for Research on Epstein-Barr Virus and Associated Diseases, Regensberg, Germany. Smith, G.J., Huss, W.J., Gray, D.R., Glover, W.J., and Werdin, E.S. (2004) Role of tissue microenvironment in determining prostate cancer phenotype. Proc. Am. Assoc. Cancer Res. 45:2785a. Smith, G.J., Huss, W.J., Gray, D.R., Werdin, E.S., and Glover, W.J. (2004) Role of tissue microenvironment in determining prostate cancer phenotype. Soc. Basic Urologic Res., Savannah, GA. Sundberg, L.J., Doherty, J.T., Mack, C.P., and Taylor, J.M. (2004) Adhesion signaling induces an association between Erk2 and Pak1 in vascular smooth muscle cells: Pak1 may serve as a scaffold for the components of an ERK cascade in adhesion complexes. International Vascular Biology Meeting, Toronto, Canada. Whitley, B.R., and Church, F.C. (2004) Rho-kinase, PI3K, and p38 signal pathways regulate ovarian cancer cell (SKOV-3) migration and invasion. Proc. Am. Assoc. Cancer Res. 45:4918a. Xu, L., Nichols, T.C., McCorquodale, S., Dillow, A, Merricks, E., and Ponder, K.P. (2004) DDAVP-induced increase in factor VIII activity in blood is likely due to release of factor VIII that is synthesized by endothelial cells. Blood 104:199a. |
| Abstracts
and Presentations from 2003
Beaulieu, L.M., Whitley, B.R., Rehault, S.M., Varner, C.E., and Church, F.C. (2003) Activated Protein C enhances breast cancer metastatic properties. FASEB J. 17:A1345. Boggess, J.F., Zhou, C., Lewis, T.D., and Whang, Y.E. (2003) The PTEN tumor suppressor inhibits telomerase activity in endometrial cancer cells by decreasing the hTERT mRNA level. Proceed. Am. Asso. Cancer Res. 44:1189a. Bushman, J.E., Ciavatta, D.J., Smithies, O., and Kirby, S.L. (2003) Lineage-restricted fluorescent transgenes as a means to track hematovascular differentiation from murine embryonic stem cells. FASEB J. 17:A686. DelBove, J.N., Knudson, E.S., Strobeck, M.W., and Weissman, B.E. (2003) Characterization of the loss of BAF155 of the SWI/SNF chromatin remodeling complex inhuman cancer cell lines. Proceed. Am. Asso. Cancer Res. 44: Fischer, T.H., Russell, K.E., Merricks, E.P., Nichols, T.C., and Bode, A.P. (2003) The development of pro-hemostatic lyophilized platelets with minimized risk for intravascular coagulation. J. Thrombosis Haemostasis 1: Gray, D.R., Werdin, E.S., Huss, W.J., Funkhouser, W.K., Mohler, J.L., and Smith, G.J. (2003) Angiogenesis in prostate and renal cell carcinomas: A novel model using primary human organ xenografts. Proc. Am. Asso. Cancer Res. 44:1342a. Huss, W.J., Gray, D.R., Werdin, E.S., Funkhouser, W.K., Mohler, J.L., and Smith, G.J. (2003) Prostate cell differentiation in response to androgen deprivation. Proc. Am. Asso. Cancer Res. 44:988a. Jahn, J.E., Ricketts, S.L., and Coleman, W.B. (2003) Transcription mapping of microcell hybrid cell lines identifies SYT13 as a candidate liver tumor suppressor gene from human 11p11.2. FASEB J. 17:A673. Khan, M.A., Crofton, K.M., Sen, B., Wolf, D.C., and Hester, S.D. (2003) Changes in gene expression profile following short-term exposure to an environmentally relevant mixture of PHAHs. Toxicologic Pathology (In Press). Khan, M.A., Crofton, K.M., Sen, B., Wolf, D.C., and Hester, S.D. (2003) Use of gene profiling to differentiate a carcinogenic from a noncarcinogenic aldehyde in the rat nose. Toxicologic Pathology (In Press). King, L.C., Adams, L.D., Winkfield, E., Hester, S.D., Barnes, J.A., and Allen, J.W. (2003) Analysis of benzo[a]pyrene-induced DNA adducts in MCF-7 breast cancer cells with different levels of HSP70 expression. Proc. Am. Asso. Cancer Res. 44:1215a. Lucas, N.C., Ryan, J.L., Butz, G.M., White, K.K., Tsongalis, G.J., Zander, D.S., and Coleman, W.B. (2003) Molecular discrimination of multiple squamous cell carcinomas: Determination of lineage relationships between cancers of the lung and head/neck. FASEB J. 17:A1190. Newberry, S.T., White, K.K., and Coleman, W.B. (2003) Methylation analysis of the BRCA1 promoter in human breast cancer cell lines. FASEB J. 17:A673. Olsen, E.H.N., McCain, A.S., Merricks, E.P., Fischer, T., Dillon, I.M., Raymer, R.A., Fahs, S.A., Montgomery, R.R., Keith, J.C., Schaub, R.G., and Nichols, T.C. (2003) Comparative responses of plasma VWF in normal and von Willebrand disease dogs to up-regulation of VWF mRNA by interleukin-11 versus Weibel-Palade body release by desmopressin (DDAVP). J. Thrombosis Haemostasis 1: Ricketts, S.L., Jahn, J.E., Carter, J.C., Theise, N.D., Conner, E.A., Thorgeirsson, S.S., Grisham, J.W., and Coleman, W.B. (2003) Chromosome 11p11.2 allelotype in human hepatocellular carcinoma. FASEB J.17:A256. Ryan, J.L., Fan, H., Raab-Traub, N., and Gulley, M.L. (2003) Cell free EBV DNA is usually not encapsidated in patients with EBV-related malignancies. FASEB J. 17:A1191. Sundberg, L.J., Bill, H.M., and Taylor, J.M. (2003) An endogenous inhibitor of focal adhesion kinase blocks Rac1/JNK but not Ras/ERK signaliing in vascular smooth muscle cells. FASEB J. 17:A1081. White, K.K., Newberry, S.T., Henderson, C.N., and Coleman, W.B. (2003) Epigenetic regulation of gene expression in human breast cancer cell lines. FASEB J. 17:A672. Whitley, B.R. and Church, F.C. (2003) Modulation of cancer cell migration and invasion by plasminogen activator inhibitor-1 (PAI-1). Proc. Am. Asso. Cancer Res. 44:760a. |
| Abstracts
and Presentations from 2002
Astern, J.M., Butz, G.M., Grisham, J.W., and Coleman, W.B. (2002) Expression of cytokine and other immediate early Genes after partial hepatectomy in retrorsine-exposed rats. FASEB J. 16:A365. Betz, B.L., Strobeck, M.W., Reisman, D.N., Knudson, E.S., and Weissman, B.E. (2002) Reexpression of hSNF5/INI1 in pediatric tumor cells induces growth arrest. Proc. Am. Asso. Cancer Res. 43:620. Bushman, J.E., Mauriello, C.T., Walton, W.G., McKinnon, K.P., Serody, J.S., and Kirby, S.L. (2002) Effects of a truncated erythropoietin receptor (tEpoR) transgene on proliferation and function of dendritic cells derived from murine bone marrow. American Society of Hematology, Philadelphia. PA. Gray, D.R., Werdin, E.S., Durham, L.E., Yau, J.M., Huss, W.J., Funkhouser, Jr., W.K., Mohler, J.L., and Smith, G.J. (2002) Angiogenesis in CaP: Primary human prostate xenografts a Novel model. Soc. Basic Urologic Res., Tuscon, AZ. Huss, W.J., Werdin, E.S., Gray, D.R., Funkhouser, Jr., W.K., Mohler, J.L., and Smith, G.J. (2002) Response to androgen deprivation in primary human prostate xenografts. Soc. Basic Urologic Res., Tuscon, AZ.. Heffernan, T.P., Simpson, D.A., Frank, A.R., Heinloth, A.N., Paules, R.S., Cordiero-Stone, M, and Kaufmann, W.K. (2002) An ATM-independent caffeine-sensitive S checkpoint inhibits replicon initiation following UVC-induced DNA damage. Keystone Symposia on Molecular Mechanisms of DNA Replication and Recombination, Snowbird, UT. Heffernan, T.P., Simpson, D.A., Frank, A.R., Heinloth, A.N., Paules, R.S., Cordiero-Stone, M, and Kaufmann, W.K. (2002) An ATR-dependent S checkpoint inhibits replicon initiation followingeckpoint inhibits replicon initiation following UVC-induced DNA damage. 55th Annual Symposium on Fundamental Cancer Research: Maintenance of Genomic Integrity, M.D. Anderson Cancer Center, University of Texas, Houston, TX. Heffernan, T.P., Simpson, D.A., Frank, A.R., Heinloth, A.N., Paules, R.S., Cordiero-Stone, M, and Kaufmann, W.K. (2002) An ATR-dependent and Chk1-dependent S checkpoint inhibits replicon initiation following UVC-induced DNA damage. The Cell Cycle, Salk Institute, La Jolla, CA. Hester, S.D., Barnes, J., Winkfield, E., and Allen, J. (2002) Profiles of gene expression associated with tetracycline-regulated expression of HSP70 in MCF-7 breast cancer cells. Proc. Am. Asso. Cancer Res. 43:454a. Nelson, L.M., Hall, J.E., and Tidwell, R.R. (2002) Detection and quantitation of anti-trypanosomal diamidine compounds in murine brain tissue. Am. J. Trop. Med. Hyg. (In Press). Pendergraft, W.F., Rudolph, E.H., Falk, R.J., Jennette, J.C., and Preston, G.A. (2002) PR3 released from neutrophils and monocytes during inflammation enters endothelial cells and cleaves p21Cip1/WAF1 at a signature site independent of that utilized by caspase 3. American Society of Nephrology, Philadelphia, PA. Preston, G.A., Pendergraft, W.F., Yang, J.J., Jennette, J.C., and Falk, R.J. (2002) Novel effects of inflammatory cell proteases on vascular endothelia. 10th International ANCA Workshop, Cleveland Clinic, Cleveland, OH. Preston, G.A., Pendergraft, W.F., Yang, J.J., Jennette, J.C., and Falk, R.J. (2002) Inflammatory cell proteases and their effects on the vascular endothelia. Keystone Symposia on Protein Phosphorylation and Mechanisms of Cellular Regulation, Taos, NM. Ricketts, S.L., Carter, J.C., Thorgeirsson, S.S., Grisham, J.W., and Coleman, W.B. (2002) Evaluation of candidate liver tumor suppressor transcripts from human chromosome 11p11.2-p12 in human hepatocellular carcinoma cell lines. FASEB J. 16:A1105. Ricketts, S.L., Carter, J.C., and Coleman, W.B. (2002) Identification of three candidate liver tumor suppressor genes from human chromosome 11p. Proc. Am. Asso. Cancer Res. 43:287a. Roper, K.I., Whitley, B.R., Ma, A., and Church, F.C. (2002) Effect of polyphenols on breast cancer cell proliferation, adhesion, and migration. FASEB J. 16:A143. Ryan, J.L., Howell, J.A., Tsongalis, G.J., and Coleman, W.B. (2002) Molecular discrimination of multiple primary and metastatic lung cancers. FASEB J. 16:A1105. Whitley, B.R. and Church, F.C. (2002) Plasminogen activator inhibitor-1 alters the metastatic potential of breast cancer cells. FASEB J. 16:A366. Whitley, B.R. and Church, F.C. (2002) Plasminogen activator inhibitor-1 alters the metastatic potential of breast cancer cells. Third International Symposium on Serpin Biology, Structure, and Function, Chicago, IL. Whitley, B.R. and Church, F.C. (2002) Plasminogen activator inhibitor-1 alters the metastatic potential of breast cancer cells. American Association for Cancer Research Edward A. Smuckler Memorial Workshop on the Pathobiology of Cancer Workshop, Keystone, CO. Yamada, N.A. and Farber, R.A. (2002) Overexpression of pol-beta increases microsatellite mutation rates in cultured cells. Proceed. Am. Asso. Cancer Res.43:695a. |
| Abstracts
and Presentations from 2001
Betz, B.L., DeCristofaro, M.F., Wang, W., and Weissman, B.E. (2001) Identification and functional consequences of hSNF5 alteration in pediatric malignancies. Proc. Am. Asso. Cancer Res. 42:321a. Deming, P.B. and Kaufmann, W.K. (2001) ATR and BRCA1 are required for the decatenation G2 check-point. Proc. Am. Asso. Cancer Res. 42:257a. Deming, P.B. and Kaufmann, W.K. (2001) An ATR- and BRCA1-dependent G2 checkpoint monitors the status of chromatid decatenation in human cells. Salk Institute Cell Cycle Meeting, La Jolla, CA. Gordon, G.J., Grisham, J.W., and Coleman, W.B. (2001) Isolation, culture, and transplantation of small hepatocyte-like progenitor cells obtained from retrorsine-exposed rats. FASEB J. 15:A1084. Henry, A.T., Alzos, J.N., Daley, G., Cargill, M., Lander, E., and Church, F.C. (2001) Characterization of single nucleotide polymorphisms (SNPs) in protein C inhibitor. FASEB J. 15:A176. Hester, S.D., Benavides, G.B., Sartor, M., Yoon, L., Morgan, K.T., and Wolf, D.C. (2001) Identification of the role of apoptosis pathways potentially involved in formaldehyde-induced carcinogenesis using cDNA microarrays. 21st Annual Joint Meeting of the Society of Toxicologic Pathologists and the International Federation of the Society of Toxicologic Pathology, Orlando, FL. Hester, S.D., Benavides, G.B., Sartor, M., Yoon, L., Morgan, K.T., and Wolf, D.C. (2001) Normal nasal gene expression levels using cDNA array technology. Proc. Am. Asso. Cancer Res. 42:606a. Hester, S.D., Benavides, G.B., Sartor, M., Yoon, L., Morgan, K.T., and Wolf, D.C. (2001) Studies of normal nasal gene expression levels in the rat nasal epithelium using cDNA array technology. AACR Special Conference on Oncogenomics, Tucson, AZ. Lininger, R.A., Nelson, L., Ding, X., Sarwar, S., Sciarrotta, J., Tavassoli, F., and Kaufman, D. (2001) Expression of Ki-67, BRCA1, BRCA2, ATM, p53, and bcl-2 in matched primary and recurrent breast carcinomas after radiation therapy. Proc. Am. Asso. Cancer Res. 42:523a. Palmieri, D., Lee, J.W., Juliano, R.L., and Church, F.C. (2001) Role of plasminogen activator inhibitors on breast cancer cell adhesion and motility. Proc. Am. Asso. Cancer Res. 42:947a. Palmieri, D., Lee, J.W., Juliano, R.L., and Church, F.C. (2001) Expression of plasminogen activator inhibitor-type 1 (PAI-1) and 3 (PAI-3) increase cell adhesion and motility in MDA-MB435 breast cancer cells. XVIIIth International Congress on Thrombosis and Haemostasis, Paris, France. Paules, R.S., Innes, C.L., Sieber, S.O., Shackleford, R.E., Heinloth, Deming, P., Cistulli, C.A., Bennett, L., Bushel, P.R., Afshari, C.A., and Kaufmann, W.K. (2001) ATM-dependent responses to DNA damaging agents. Keystone Oncogenomics Symposium, Keystone, CO. Ricketts, S.L., Garcia, N.F., and Coleman, W.B. (2001) Identification of candidate liver tumor suppressor genes from human 11p11.2-p12. Proc. Am. Asso. Cancer Res. 42:629a. Tepper, S., Butz, G.M., Grisham, J.W., and Coleman, W.B. (2001) Methylation of the BRCA1 promoter accounts for loss of gene expression during rat hepatocarcinogenesis. FASEB J. 15:A1181. Tepper, S. and Coleman, W.B. (2001) Expression of multiple DNA methyltransferases is not sufficient for expression of a DNA methylation mutator phenotype and gene-specific methylation in sporadic breast cancer. Proc. Am. Asso. Cancer Res. 42:494a. Whitley, B., Palmieri, D., and Chrurch, F.C. (2001) Effect of plasminogen activator inhibitor (PAI)-1 and PAI-3 on MDA-MB-435 breast tumor cell proliferation. FASEB J. 15:A251. Yamada, N.A., Boyer, J.C., Roques, C.N., and Farber, R.A. (2001) Spontaneous mononucleotide and dinucleotide mutation rates of telomerase-expressing normal human fibroblasts. Proc. Am. Asso. Cancer Res. 42:902a. Yamada, N.A., Castro, A., and Farber, R.A. (2001) Different microsatellite mutation rates in cancer cell lines with defects in different mismatch repair genes. Am. J. Human Genetics 69:538a. Zarella, C.S., Pendergraft, W.F., Falk, R.J., and Preston, G.A. (2001) Proteinase 3/Myeloblastin induces a burst of proliferation in endothelial cells. American Society of Nephrology, San Francisco, CA. |
| Abstracts
and Presentations from 2000
Kaufmann, W.K., Campbell, C., Simpson, D., Boucher, P., Paules, R., Innes, C., Shackleford, R., Piwinca-Worms, H., Zhao, X., Joyce, K, and Downes, S. (2000) The catenation-sensitive G2 checkpoint in human cells is independent of ATM or p53 signalling. Keystone Symposia on Cancer, Cell Cycle, and Therapeutics, Keystone, CO. Gordon, G.J., Coleman, W.B., and Grisham, J.W. (2000) Induction of specific cytochrome P450 isoforms in rat liver after exposure to the pyrrolizidine alkaloid retrorsine. FASEB J. 14:A175. Gordon, G.J., Coleman, W.B., and Grisham, J.W. (2000) Early-appearing small hepatocyte-like progenitor cells in the retrorsine model of hepatocellular injury and regeneration lack expression of cytochrome P450 enzymes. FASEB J. 14:A285. Gordon, G.J., Coleman, W.B., and Grisham, J.W. (2000) Bax-mediated apoptosis of retrorsine-injured hepatocytes during liver regeneration after partial hepatectomy in retrorsine-treated rats. FASEB J. 14:A554. Hester, S.D., Wolf, D.C., Benavides, G., and Morgan, K.T. (2000) A method for harvesting respiratory/transitional epithelial cell RNA from the anterior nasal passages of rats. Toxicologic Sciences (In Press) Hodgin, J.B., Krege, J.H., Korach, K.S., and Maeda, N. (2000) Estrogen receptor a mediates estrogen's atheroprotective effect. FASEB J. 14:A455. Kaufmann, W.K., Campbell, C., Simpson, D., Boucher (Deming), P., Paules, R., Innes, C., Shackleford, R., Piwinca-Worms, H., Zhao, X., Joyce, K, and Downes, S. (2000) The catenation-sensitive G2 checkpoint in human cells is independent of ATM or p53 signalling. Keystone Symposia on Cancer, Cell Cycle, and Therapeutics, Keystone, CO. Patel, A.C., Foley, J.F., Stockton, P.S., Barrett, J.C., and Devereaux, T.R. (2000) Expression and hypermethylation of p16INK4A in laser capture microdissected B6C3F1 mouse lung tumors. Proc. Am. Asso. Cancer Res. 41:78A. Pendergraft, W.F., Zarella, C.S., Yang, J.J., Falk, R.J., Jennette, J.C., and Preston, G.A. (2000) Proteolytically inactive C-terminal death domain of Proteinase 3.Ninth International ANCA Workshop (Groningen, The Netherlands). Pereira, A., Eron, J.J., Dunn, J., Gerber, R., Tidwell, R., Kenney, K., et al. (2000) Analysis of amprenavir, 3TC/AZT in blood and seminal plasma: Penetration of amprenavir into the male genital tract. 7th Conference on Retroviruses and Opportunistic Infections. Pereira, A., Eron, J.J., Dunn, J., Gerber, R., Tidwell, R., Kenney, K., et al. (2000) Amprenavir, Lamivudine and Zidovudine in blood and seminal plasma. 1st International Workshop on Clinical Pharmacology of HIV Therapy. Pereira, A. (2000) Measuring protease inhibitors in seminal plasma. 1st International Workshop on Clinical Pharmacology of HIV Therapy. Rider, M.A., Grisham, J.W., and Coleman, W.B. (2000) Suppression of the tumorigenic phenotype of a rat liver epithelial tumor cell line following microcell-mediated introduction of human chromosome 13. FASEB J. 14:A286. Tepper, S., Ricketts, S.L., Grisham, J.W., and Coleman, W.B. (2000) Epigenetic regulation of tumor suppressor gene expression in a rat liver tumor cell line in vitro. FASEB J. 14:A447. Yang, J.J., Preston, G.A., Pendergraft, W.F., Heeringa, P., Jennette, J.C., and Falk, R.J. (2000) Internalization of PR3 is concomitant with endothelial cell damage. Ninth International ANCA Workshop (Groningen, The Netherlands). Zarella, C.S., Pendergraft, W.F., Yang, J.J., Falk, R.J., and Preston, G.A. (2000) Signal Transduction Pathways Modulated by Proteinase 3 Treatment. Ninth International ANCA Workshop (Groningen, The Netherlands). Zarella, C.S., Pendergraft, W.F., Yang, J.J., Falk, R.J., and Preston, G.A. (2000) Caspase-like activity of Proteinase 3: A mechanism of endothelial cell death during inflammation. American Society of Nephrology, Toronto, Canada. |
| Abstracts
and Presentations from 1999
Arnold, J.T., Lessey, B.A., and Kaufman, D.G. (1999) Regulation of growth and differentiation of Ishikawa endometrial adenocarcinoma cells by endometrial stromal cells and extracellular matrix. Proceed. Am. Asso. Cancer Res. 40:504a. Boucher (Deming), P.M., Palmieri, D., and Church, F.C. (1999) Expression of plasminogen activator inhibitors in gynecologic cancers. Thrombosis and Haemostasis 81(Suppl 1):A160. Bullock, S.K., Kaufmann, W.K., and Cordeiro-Stone, M. (1999) DNA replication in UV-damaged xeroderma pigmentosum variant (XP-V). Photochem. Photobiol. 69:94S. Bushman, J.E., Palmieri, D., Whinna, H.C., and Church, F.C. (1999) Insight into the mechanism of asparaginase-induced depletion of antithrombin III in treatment of childhood acute lymphoblastic leukemia. Thrombosis and Haemostasis 81:A159. Filatov, L., Cistulli, C.A., and Kaufmann, W.K. (1999) G2 Chromosomal hypersensitivity in breast cancer and lymphoblastoid cell lines with different ATM status. 31st Annual Meeting of the European Society of Human Genetics, Volume 7, Supplement 1, July 1999. Dawson, T.C., Beck, M.A., Kuziel, W.A., and Maeda, N. (1999) Chemokine regulation of the cellular response to influenza A virus. FASEB J. 13:A819. Dawson, T.C., Kuziel, W.A., and Maeda, N. (1999) Roles of CCR2 and CCR5 in atherosclerotic plaque formation in apolipoprotein E-deficient mice. Keystone Symposia on Chemokine and Chemokine Receptors, Keystone, CO. Gordon, G.J., Coleman, W.B., Hixson, D.C., and Grisham, J.W. (1999) Cellular responses during liver regeneration after partial hepatectomy in rats with retrorsine-induced hepatocellular injury. FASEB J. 13: A189. Gordon, G.J., Coleman, W.B., and Grisham, J.W. (1999) Transplantation of WB-F344 stem-like cells into rats following retrorsine-induced hepatocellular injury. FASEB J. 13: A160. Gorkun, O.V., Mullin, J.L., Hogan, K.A., and Lord, S.T. (1999) Alanine 68 of the Bb chain has an important role in polymerization. Thrombosis and Haemostasis 81(Suppl. 1):A131. Hogan, K.A., and Lord, S.T. (1999) Polymerization of a recombinant fibrinogengD319,320, the deletion discovered in a heterozygous individual. FASEB J. 13:A516. Palmieri, D., Boucher, P.M., and Church, F.C. (1999) Serpin expression in malignant human tissues and in gynecologic cancer cell lines. 2nd International Symposium on the Structure and Biology of Serpins, Cambridge, England. Patel, A.C., Tyson, F.L., Barrett, J.C., and Devereux, T.R. (1999) Hypermethylation of p16Ink4a in mouse lung tumor cell lines. Proceed. Am. Asso. Cancer Res. 40:A441. Pendergraft, W.F., Yang, J.J., Falk, R.J., Jennette, J.C., and Preston, G.A. (1999) An enzymatically inactive domain of Proteinase 3 with apoptotic function. Leiden International Medical Students Conference (Leiden, The Netherlands). Pendergraft, W.F., Yang, J.J., Falk, R.J., Jennette, J.C., and Preston, G.A. (1999) Identification of a non-catalytic domain of Proteinase 3 with apoptotic function. 32nd Annual Meeting, American Society of Nephrology (Miami Beach, Florida). Ricketts, S.L., Garcia, N.F., Reid, L.H., and Coleman, W.B. (1999) Identification of candidate human 11p11.2-p12 liver tumor suppressor genes through transcription mapping of expressed sequence tags. FASEB J. 13:A191. Ricketts, S.L., Fox, D.R., Glover, W.J., Smith, G.J., Grisham, J.W., and Coleman, W.B. (1999) Expression of the KTS splice variant of WT1 alters cell phenotype in vitro but incompletely regulates tumorigenicity in vivo in rat liver epithelial tumor cell lines. FASEB J. 13:A161. Rider, M., Gordon, G.J., Grisham, J.W., and W.B. Coleman (1999) Optimization of rat liver stem-like cell transplantation efficiency. FASEB J. 13:LB394. Segelmark, M., Barrett, C.V., Pendergraft, W.F., Falk, R.J., and Preston, G.A. (1999) Elucidation of a role for p300 in the regulation of apoptosis in rat mesangial cells. 32nd Annual Meeting, American Society of Nephrology (Miami Beach, Florida). Tepper S., Ricketts S.L., Grisham J.W., and Coleman W.B. (1999) Clonal analysis of tumor suppressor geneexpression among carcinogen-transformed rat liver epithelial cell lines and derived tumors. FASEB J. 13:LB166. Wemhoff, J.L. and Church, F.C.(1999) Functional role of the acidic domain of heparin cofactor II. FASEB J. 13:A517. Wemhoff, J.L. and Church, F.C. (1999) Role of acidic residues in the second acidic domain of heparin cofactor II (HCII) during thrombin inhibition. Blood 94:A2039. Yang, J.J., Preston, G.A., Segelmark, M., Pendergraft, W.F., Jennette, J.C., and Falk, R.J. (1999) Proteinase 3 translocation into cells is necessary for triggering apoptosis. 32nd Annual Meeting, American Society of Nephrology (Miami Beach, Florida). |
| Abstracts
and Presentations from 1998
Gordon, G., Seaman, T., Read, M.S., Bellinger, D.A., Coleman, W.B., and Nichols, T. (1998) Transgenic hepatocyte expression of human von Willibrand factor (vWF) in mice. FASEB J. 12:A191. Ricketts, S.L., Smith, G.J., Grisham, J.W., and Coleman, W.B. (1998) Hepatocyte-specific gene expression in differentiating WB-F344 rat liver stem-like epithelial cells cultured in the presence of sodium butyrate. FASEB J. 12:A469. Tarka, D.K., Torti, V.R., and Kaufman, D.G. (1998) Characterization of proteins involved in epithelial-stromal interactions and the effects on endometrial cancer and aging. Society for In Vitro Biology, Las Vegas, NV. |
| Abstracts
and Presentations from 1997
Rinehart, C.A., Torti, V.R., Palmieri, D., Novotny, D.B., Kaufman, D.G., and Watson, J.M. (1997) The role of aging in hormonal carcinogenesis. Gordon Research Conference, Nashua, NH. Torti, V.R., He, X., Van Le, L., Novotny, D.B., Kaufman, D.G., and Rinehart, C.A. (1997) Regulation of epithelial cell growth by IL-1 and its role in age-related carcinogenesis. Proceed. Am. Asso. Cancer Res. |
| Abstracts
and Presentations from 1996
Torti, V.R., Rinhart, C.A., and Kaufman, D.G. (1996) Age-regulated paracrine control of epithelial cells by human endometrial stromal cells. FASEB J. 10:A1146. |
| Abstracts
and Presentations from 1995
Torti, V.R., Rinhart, C.A., and Kaufman, D.G. (1995) In vitro evidence for epithelial influence on paracrine interactions between human endometrial stromal and epithelial cells. Mol. Biol. Cell 6:219a. |