Altenburg, M., Johnson, L., Wilder, J., and Maeda, N. (2007) Apolipoprotein E4 in macrophages enhances atherogenesis in a low density lipoprotein receptor-dependent manner. J. Biol. Chem. 282:7817-7824.

Astern, J.M., Pendergraft, W.F., 3rd, Falk, R.J., Jennette J.C., Schmaier, A.H., Mahdi, F., and Preston, G.A. (2007) Myeloperoxidase interacts with endothelial cell-surface cytokeratin 1 and modulates bradykinin production by the plasma Kallikrein-Kinin system. Am. J. Pathol. 171:349-360.

Beaulieu, L.M. and Church, F.C. (2007) Activated protein C promotes breast cancer cell migration through interactions with EPCR and PAR-1. Exp. Cell Res. 313:677-687.

Best, D.H. and Coleman, W.B. (2007) Treatment with 2-AAF blocks the small hepatocyte-like progenitor cell response in retrorsine-exposed rats.  J. Hepatol. 46:1055-1063.

Best, D.H. and Coleman, W.B. (2007)  Bile duct destruction by 4,4’-diaminodiphenylmethane does not block the small hepatocyte-like progenitor cell response in retrorsine-exposed rats.  Hepatology (In Press).

Best, D.H. and Coleman, W.B. (2007) Cells of origin of small hepatocyte-like progenitor cells in the retrorsine model of rat liver injury and regeneration.  J. Hepatology (In Press).

Campbell, R.A., Fischer, T.H., and Wolberg, A.S. (2007) A novel approach to improving recombinant factor VIIa activity with a preserved platelet preparation. Br. J. Haematol. 138:82-93.

Chai, J., Lu, X., Godfrey, V., Fletcher, C., Roberts, C.W., Van Dyke, T., and Weissman, B.E. (2007) Tumor-specific cooperation of retinoblastoma protein family and Snf5 inactivation. Cancer Res. 67:3002-3009.

Gilner, J.B., Walton, W.G., Gush, K., and Kirby, S.L. (2007) Antibodies to stem cell marker antigens reduce engraftment of hematopoietic stem cells. Stem Cells 25:279-288.

Goedken, M., McCormick, S., Leidal, K.G., Suzuki, K., Kameoka, Y., Astern, J.M., Huang, M., Cherkasov, A., Nauseef, W.M. (2007) Impact of two novel mutations on the structure and function of human myeloperoxidase. J. Biol. Chem. (In Press). 

Hakim, Z.S., DiMichele, L.A., Doherty, J.T., Homeister, J.W., Beggs, H.E., Reichardt, L.F., Schwartz, R.J., Brackhan, J., Smithies, O., Mack, C.P., Taylor, J.M. (2007) Conditional deletion of focal adhesion kinase leads to defects in ventricular septation and outflow tract alignment. Mol. Cell. Biol. 27:5352-5364.

Hall, J.R., Kow, E., Nevis, K.R., Lu, C.K., Luce, K.S., Zhong, Q., and Cook, J.G. (2007) Cdc6 stability is regulated by the Huwe1 ubiquitin ligase after DNA damage.  Mol. Biol. Cell. 18:3340-3350.

Heffernan, T.P., Unsal-Kacmaz, K., Heinloth, A.N., Simpson, D.A., Paules, R.S., Sancar, A., Cordeiro-Stone, M., Kaufmann, W.K. (2007) Cdc7-Dbf4 and the human S checkpoint response to UVC. J. Biol. Chem. 282:9458-9468.

Hinson, J.S., Medlin, M.D., Lockman, K., Taylor, J.M., and Mack, C.P. (2007) Smooth muscle cell-specific transcription is regulated by nuclear localization of the myocardin-related transcription factors. Am. J. Physiol. - Heart. Circ. Physiol. 292:H1170-1180.

Kaufmann, W.K., Nevis, K.R., Qu, P., Ibrahim, J.G., Zhou, T., Zhou, Y., Simpson, D.A., Helms-Deaton, J., Cordeiro-Stone, M., Moore, D.T., Thomas, N.E., Hao, H., Liu, Z., Shields, J.M., Scott, G.A., Sharpless, N.E. (2007) Defective cell cycle checkpoint functions in melanoma are associated with altered patterns of gene expression. J. Invest. Dermatol. (In Press). 

Lucic, D., Huang, Z.H., de Gu, S., Altenburg, M.K., Maeda, N., Mazzone, T. (2007) Regulation of macrophage apoE secretion and sterol efflux by the LDL receptor. J. Lipid Res. 48:366-372.

Muallem, H., North, K.E., Kakoki, M., Wojczynski, M.K., Li, X., Grove, M., Boerwinkle, E.,Wilhelmsen, K.C., Heiss, G., and Maeda, N.  (2006) Quantitative effects of common genetic variations in the 3'UTR of the human LDL-receptor gene and their associations with plasma lipid levels in the Atherosclerosis Risk in Communities study. Human Genet. 121:421-431.

Nichols, T.C., Busby, W.H., Jr, Merricks, E., Sipos, J., Rowland, M., Sitko, K., and Clemmons, D.R. (2007)  Protease resistant IGFBP-4 inhibits IGF-I actions and neointimal expansion in a porcine model of neointimal hyperplasia.  Endocrinology (In Press). 

Rau, J.C., Beaulieu, L.M., Huntington, J.A., and Church, F.C. (2007) Serpins in thrombosis, hemostasis and fibrinolysis. J. Thromb. Haemost. 5:102-115.

Staus, D.P., Blaker, A.L., Taylor, J.M., and Mack, C.P. (2007) Diaphanous 1 and 2 regulate smooth muscle cell differentiation by activating the myocardin-related transcription factors. Arterioscler. Thromb. Vasc. Biol. 27:478-486.

Whitley, B.R., Beaulieu, L.M., Carter, J.C., and Church, F.C. (2007) Phosphatidylinositol 3-kinase/Akt regulates the balance between plasminogen activator inhibitor-1 and urokinase to promote migration of SKOV-3 ovarian cancer cells. Gynecol. Oncol. 104:470-479.

Zhou, T., Chou, J., Mullen, T.E., Elkon, R., Zhou, Y., Simpson, D.A., Bushel, P.R., Paules, R.S., Lobenhofer, E.K., Hurban, P., and Kaufmann, W.K. (2007) Identification of primary transcriptional regulation of cell cycle-regulated genes upon DNA damage. Cell Cycle6:972-981.

Bellinger, D.A., Merricks, E.P., and Nichols, T.C. (2006) Swine models of type 2 diabetes mellitus: Insulin resistance, glucose tolerance, and cardiovascular complications. ILAR J. 47:243-258.

Charboneau, A., Chai, J., Jordan, J., Funkhouser, W., Judkins, A., Biegel, J., and Weissman, B. (2006) P-Akt expression distinguishes two types of malignant rhabdoid tumors. J. Cell. Physiol. 209:422-427.

Chastain, P.D., 2nd, Heffernan, T.P., Nevis, K.R., Lin, L., Kaufmann, W.K., Kaufman, D.G., and Cordeiro-Stone, M. (2006) Checkpoint regulation of replication dynamics in UV-irradiated human cells. Cell Cycle 5:2160-2167.

DiMichele, L.A., Doherty, J.T., Rojas, M., Beggs, H.E., Reichardt, L.F., Mack, C.P., and Taylor, J.M. (2006) Myocyte-restricted focal adhesion kinase deletion attenuates pressure overload-induced hypertrophy. Circ. Res. 99:636-645.

Dumont, D., Behler, R.H., Nichols, T.C., Merricks, E.P., and Gallippi, C.M. (2006) ARFI imaging for noninvasive material characterization of atherosclerosis. Ultrasound Med. Biol. 32:1703-1711.

Fischer, T.H., Bode, A.P., Parker, B.R., Russell, K.E., Bender, D.E., Ramer, J.K., and Read, M.S. (2006) Primary and secondary hemostatic functionalities of rehydrated, lyophilized platelets. Transfusion 46:1943-1950.

Innes, C.L., Heinloth, A.N., Flores, K.G., Sieber, S.O., Deming, P.B., Bushel, P.R., Kaufmann, W.K., and Paules, R.S. (2006) ATM requirement in gene expression responses to ionizing radiation in human lymphoblasts and fibroblasts.  Mol. Cancer Res. 4:197-207.

Rivenbark, A.G., Jones, W.D., Risher, J.D., and Coleman, W.B. (2006) DNA methylation-dependent epigenetic regulation of gene expression in MCF-7 breast cancer cells.  Epigenetics 1:32-44.

Ryan, J.L., Kaufmann, W.K., Raab-Traub, N., Oglesbee, S.E., Carey, L.A., and Gulley, M.L. (2006) Clonal evolution of lymphoblastoid cell lines. Lab. Invest. 86:1193-1200.

Tsai, Y.S., Pendse, A., Moy, S.S., Mohri, I., Perez, A., Crawley, J.N., Suzuki, K., and Maeda, N. (2006) A de novo deafwaddler mutation of Pmca2 arising in ES cells and hitchhiking with a targeted modification of the PPARg gene. Mamm. Genome 17:716-722.

Zhou, T., Chou, J.W., Simpson, D.A., Zhou, Y., Mullen, T.E., Medeiros, M., Bushel, P.R., Paules, R.S., Yang, X., Hurban, P., Lobenhofer, E.K., Kaufmann, W.K. (2006)  Profiles of global gene expression in ionizing-radiation-damaged human diploid fibroblasts reveal synchronization behind the G1 checkpoint in a G0-like state of quiescence. Environ. Health Perspect. 114:553-559.

Brunetti-Pierri, N., Nichols, T.C., McCorquodale, S., Merricks, E., Palmer, D.J., Beaudet, A.L., and Ng, P. (2005) Sustained phenotypic correction of canine hemophilia B after systemic administration of helper-dependent adenoviral vector. Human Gene Therapy 16:811-820.

Chai, J., Charboneau, A.L., Betz, B.L., and Weissman, B.E. (2005) Loss of the hSNF5 gene concomitantly inactivates p21CIP/WAF1 and p16INK4a activity associated with replicative senescence in A204 rhabdoid tumor cells.  Cancer Res. 65:10192-10198.

Coleman, W.B., and Best, D.H. (2005) Cellular responses in experimental liver injury: Possible cellular origins of regenerative stem-like progenitor cells.  Hepatology41:1173-1176.

Fischer, T.H., Thatte, H.S., Nichols, T.C., Bender-Neal, D.E., Bellinger, A.D., and Vournakis, J.N. (2005) Synergistic platlet integrin signaling and factor XII activation in poly-N-acetyl glucosamine fiber-mediated hemostasis.  Biomaterials 26:5433-5443.

Glasscock, L.N., Rehault, S.M., Gregory, C.W., Cooper, S.T., Jackson, T.P., Hoffman, M., and Church, F.C. (2005) Protein C inhibitor (plasminogen activator inhibitor-3) expression in the CWR22 prostate cancer xenograft. Exp. Mol. Pathol. 79:23-32.

Gregory, C.W., Whang, Y.E., McCall, W., Fei, X., Liu, Y., Ponguta, L.A., French, F.S., Wilson, E.M., and Earp, H.S. (2005) Heregulin activation of ErbB2 and ErbB3 increases androgen receptor transactivation and CWR-R1 human recurrent prosatate cancer cell growth. Clinical Cancer Research 11:1704-1712.

Haberichter, S.L., Merricks, E.P., Fahs, S.A., Christopherson, P.A., Nichols, T.C., and Montgomery, R.R. (2005) Re-establishment of VWF-dependent Weibel-Palade bodies in VWD endothelial cells. Blood 105:145-152.

Huss, W.J., Gray, D.R., Greenberg, N.M., Mohler, J.L., and Smith, G.J. (2005) Breast cancer resistance protein-mediated efflux of androgen in putative benign and malignant prostate stem cells. Cancer Research 65:6640-6650.

Khan, M.A., Fenton, S.E., Swank, A.E., Hester, S.D., Williams, A., and Wolf, D.C. (2005) A mixture of ammonium perchlorate and sodium chlorate enhances alterations of the pituitary-thyroid axis caused by the individual chemicals in adult male F344 rats.  Toxicol. Pathol.33:776-783.

King, N.M., Nikolaishvilli-Feinberg, N., Bryant, M.F., Luche, D.L., Heffernan, T.P., Simpson, D.A., Hanaoka, F., Kaufmann, W.K., and Cordeiro-Stone, M. (2005) Overproduction of DNA polymerase eta does not raise the spontaneous mutation rate oin diploid human fibroblasts.  DNA Repair 4:714-724..

Mack, C.P. and Hinson, J.S. (2005) Regulation of smooth muscle cell differentiation by the myocardin family of serum response co-factors. J. Thromb. Haemost. 3:1976-1984.

Pendergraft, W.F., Pressler, B.M., Jennette, J.C., Falk, R.J., and Preston, G.A. (2005)  Autoantigen complementarity: Anew theory implicating complementary proteins as initiators of autoimmune disease. J. Molecular Medicine 83:12-25.

Preston, G.A., Pendergraft, W.F., and Falk, R.J. (2005) New insights that link microbes with the generation of antineutrophil cytoplasmic autoantibodies: The theory of autoantigen complementarity.  Current Opinion Nephrology Hypertension 14:217-222.

Saulter, J.Y., Kurian, J.R., Trepanier, L.A., Tidwell, R.R., Bridges, A.S., Boykin, D.W., Stephens, C.E., Anbazhagan, M, and Hall, J.E. (2005) Unusual dehydroxylation of antimicrobial amidoxime prodrugs by cytochrome b5 and NADH cytochrome b5 reductase.  Drug Metabolism Disposal. 33:1886-1893.

Simpson, D.A., Livanos, E., Heffernan, T.P., and Kaufmann, W.K. (2005) Telomerase expression is sufficient for chromosomal integrity in cells lacking p53 dependent G1 checkpoint function.  J. Carcinogenesis 4:18.

Sen, B., Wang, A., Hester, S.B., Robertson, J.L., and Wolf, D.C. (2005)  Gene expression profiling of responses to dimethylarsinic acid in female F344 rat urothelium.  Toxicology 215:214-226.

Sundberg-Smith, L.J., Doherty, J.T., Mack, C.P., and Taylor, J.M. (2005) Adhesion stimulates direct PAK1/ERK2 association and leads to ERK-dependent PAK1 Thr212 phosphorylation. J. Biol. Chem. 280:2055-2064.

Thorne, L.B., Ryan, J.L., Elmore, S.H., Glaser, S.L., and Gulley, M.L. (2005) Real-time PCR of Epstein-Barr virus in invasive breast carcinoma.  Diagnostic Molecular Pathology14:29-33.

Tsai, Y.-S. and Maeda, N. (2005) PPARgamma: A critical determinant of body fat distribution in humans and mice.  Trends Cardiovascular Medicine 15:81-85.

Unsal-Kacmaz, K, Mullen, T.E., Kaufmann, W.K., and Sancar, A. (2005) Coupling of human circadian and cell cycles by the timeless protein.  Mol. Cell Biol. 25:3109-3116.

Werner, C.G., Godfrey, V., Arnold, R.R., Featherstone, G.L., Bender, D., Schlossmann, J., Schiemann, M., Hoffmann, F., and Pryzwansky, K.B. (2005) Neutrophil dysfunction in guanosine 3’,5’-cyclic monophosphate-dependent protein kinase I-deficient mice.  J. Immunol. 175:1919-1929.

Whitley, B.R., and Church, F.C. (2005) Regulation of wound-induced migration of MDA-MB-435 and SKOV-3 cancer cells by plasminogen activator inhibitor-1.  Int. J. Oncol.27:749-757.

Zhou, T., Chou, J.W., Simpson, D.A., Zhou, Y., Mullen, T.E., Medeiros, M., Bushle, P.R., Paules, R.S., Yang, X., Hurban, P., Lobenhofer, E.K., and Kaufmann, W.K. (2005) Profiles of global gene expression in ionizing radiation-damaged human diploid fibroblasts reveal synchronization behind the G1 checkpoint in a G0-like state of quiescence. Environ. Health Perspectives114:553-559.

Best, D.H., Butz, G.M., Moller, K., Coleman, W.B., and Thomas, D.B. (2004) Molecular analysis of an immature ovarian teratoma with gliomatosis peritonei and recurrence suggests genetic independence of multiple tumors.  Int. J. Oncol. 25:17-25.

Calderon-Garciduenas, L., Reed, W., Maronpot, R., Henriquez-Roldan, C., Delgado-Chavez, R., Calderon-Garciduenas, A., Dragustinovis, I., Franco-Lira, M., Aragon-Flores, M., Solt, A., Altenburg, M., Torres-Jardon, R., and Swenberg, J. (2004) Brain inflammation and Alzheimer's-like pathology in individuals exposed to severe air pollution. Toxicol Pathol.32:650-658.

Edgell, C.J.S., BaSalamah, M.A., and Marr, H.S. (2004) Testican, a differentially expressed proteoglycan with protease inhibiting activities.  Int. Rev. Cytol. 236:101-122.

Gray, D.R., Huss, W.J., Yau, J.M., Durham, L.E., Werdin, E.S., Funkhouser, Jr., W.K., and Smith, G.J. (2004)  Short-term human prostate primary xenografts: An in vivo model of human prostate cancer vasculature and angiogenesis.  Cancer Research 64:1712-1721.

Gregory, C.W., Fei, X., Ponguta, L.A., He, B., Bill, H.M., French, F.S., and Wilson, E.M. (2004) Epidermal growth factor increases coactivation of the androgen receptor in recurrent prostate cancer.  J. Biol. Chem. 279:7119-7130.

Hogan, K.A., Merenbloom, B.K., Kim, H.S., and Lord, S.T. (2004) Neonatal bleeding and decreased plasma fibrinogen levels in mice modeled after the dysfibrinogen Vlissingen/Frankfurt IV.  J. Thrombosis Haemost. 2:1484-1487.

Huss, W.J., Gray, D.R., Werdin, E.S., Funkhouser, Jr., W.K., and Smith, G.J. (2004) Evidence of pluripotent human prostate stem cells in a human prostate primary xenograft model. TheProstate 60:77-90.

Kakoki, M., Tsai, Y.S., Kim, H.S., Hatada, S., Ciavatta, D.J., Takahashi, N., Arnold, L.W., Maeda, N., and Smithies, O. (2004) Altering the expression in mice of genes by modifying their 3' regions. Dev. Cell. 6:597-606.

Klett, E.L., Lu, K., Kosters, A., Vink, E., Lee, M.H., Altenburg, M., Shefer, S., Batta, A.K., Yu, H., Chen, J., Klein, R., Looije, N., Oude-Elferink, R., Groen, A.K., Maeda, N., Salen, G., and Patel, S.B. (2004) A mouse model of sitosterolemia: absence of Abcg8/sterolin-2 results in failure to secrete biliary cholesterol. BMC Med. 2:5.

Knouff, C., Briand, O., Lestavel, S., Clavey, V., Altenburg, M., and Maeda, N. (2004) Defective VLDL metabolism and severe atherosclerosis in mice expressing human apolipoprotein E isoforms but lacking the LDL receptor. Biochim. Biophys. Acta.1684:8-17.

Lanteri, C.A., Trumpower, B.L., Tidwell, R.R., and Meshnick, S.R. (2004) DB75, a novel trypanocidal agent, disrupts mitochondrial function in Saccharomyces cerevisiae. Antimicrob. Agents Chemother. 48:3968-3974.

Lockman, K., Hinson, J.S., Medlin, M.D., Morris, D., Taylor, J.M., and Mack, C.P. (2004) Sphingosine 1-phosphate stimulates smooth muscle cell differentiation and proliferation by activating separate serum response factor co-factors.  J. Biol. Chem. 279:42422-42430.

Malloy, S.I., Altenburg, M.K., Knouff, C., Lanningham-Foster, L., Parks, J.S., and Maeda, N. (2004) Harmful effects of increased LDLR expression in mice with human APOE*4 but not APOE*3. Arterioscler. Thromb. Vasc. Biol. 24:91-97.

Novoradovskaya, N., Whitfield, M.L., Basehore, L.S., Novoradovsky, A., Pesich, R., Usary, J., Karaca, M., Wong, W.K., Aprelikova, O., Fero, M., Perou, C.M., Botstein, D., and Braman, J. (2004) Universal Reference RNA as a standard for microarray experiments.  BMC Genomics5:20.

Pendergraft III, W.F., Preston, G.A., Shah, R.R., Tropsha, A., Jennette, J.C., and Falk, R.J. (2004) cPR-3 (105-201), a protein complementary to the human autoantigen proteinase 3, triggers autoimmunity.  Nature Medicine 10:72-79.

Pendergraft, W.F., Rudolph, E.H., Falk, R.J., Jahn, J.E., Grimmler, M., Hengst, L., Jennette, J.C., and Preston, G.A. (2004) Proteinase 3 sidesteps caspases and cleaves p21Waf1/Cip1/Sdi1 to induce endothelial cell apoptosis.  Kidney Int.  65:75-84.

Ryan, J.L., Fan, H., Glaser, S.L., Schichman, S.A., Raab-Traub, N., and Gulley, M.L. (2004) Epstein-barr virus quantitation by real-time PCR targeting multiple gene segments: a novel approach to screen for the virus in paraffin-embedded tissue and plasma. J. Mol. Diagn. 6:378-385.

Ryan, J.L., Fan, H., Swinnen, L.J., Schichman, S.A., Raab-Traub, N., Covington, M., Elmore, S., and Gulley, M.L. (2004) Epstein-Barr Virus (EBV) DNA in plasma is not encapsidated in patients with EBV-related malignancies. Diagn. Mol. Pathol. 13:61-68.

Sen, B., Wolf, D.C., and Hester, S.D. (2004) The transcriptional profile of the kidney in Tsc2 heterozygous mutant Long Evans (Eker) rats compared to wild-type.  Mutation Research 549:213-224.

Sturk, L.M., Brock, J.L., Bagnell, C.R., Hall, J.E., and Tidwell, R.R. (2004) Distribution and quantitation of the anti-trypanosomal diamidine 2,5-bis(4-amidinophenyl)furan (DB75) and its N-methoxy prodrug DB289 in murine brain tissue. Acta. Trop. 91:131-143.

Szabo, A., Perou, C.M., Karaca, M., Perreard, L., Quackenbush, J.F., and Bernard, P.S. (2004) Statistical modeling for selecting housekeeper genes.  Genome Biol. 5:R59.

Tsai, Y.S., Kim, H.J., Takahashi, N., Kim, H.S., Hagaman, J.R., Kim, J.K., and Maeda, N. (2004) Hypertension and abnormal fat distribution but not insulin resistance in mice with P465L PPARgamma. J. Clin. Invest. 114:240-249.

Usary, J., Llaca, V., Karaca, G., Presswala, S., Karaca, M., He, X., Langerod, A., Karesen, R., Oh, D.S., Dressler, L.G., Lonning, P.E., Strausberg, R.L., Chanock, S., Borresen-Dale, A.L., and Perou, C.M. (2004) Mutation of GATA3 in human breast tumors.  Oncogene 23:7669-7678.

Whang, Y.E., Yuan, X.J., Liu, J., Majumder, S., and Lewis, T.D. (2004) Regulation of sensitivity to TRAIL by the PTEN tumor suppressor. Vitamins Hormones  67:409-426.

Whitley, B.R., Palmieri, D., Twerdie, C.D., and Church, F.C. (2004) Expression of active plasminogen activator inhibitor-1 reduces cell migration and invasion in breast and gynecological cancer cells.  Exp. Cell Res. 296:151-162.

Yang, J.J., Pendergraft, W.F., Alcorta, D.A., Nachman, P.H., Hogan, S.L., Thomas, R. P. Sullivan, P., Jennette, J.C., Falk, R.J., and Preston, G.A. (2004) Circumvention of normal constraints on granule protein gene expression in peripheral blood neutrophils and monocytes of patients with antineutrophil cytoplasmic autoantibody-associated glomerulonephritis.  J. Am. Soc. Nephrol. 15:2103-2114.

Betz, B.L. and Weissman, B.E. (2003) Hybrid capture of putative tumor suppressor genes.  In: Tumor Suppressor Genes: Pathways and Isolation Strategies (El-Deiry, W.S., Ed.). Humana Press, Totowa, NJ. Methods in Molecular Biology 222:365-373.

Furmaga, W.B., Ryan, J., Coleman, W.B., Cole, S.R., and Tsongalis, G.J. (2003) Alu-Profiling of primary and metastatic non-small cell lung cancer. Exp. Mol. Pathol. 74:224-229.

Glasscock, L.N., Gerlitz, B., Cooper, S.T., Grinnell, B.W., and Church, F.C. (2003) Basic residues in the 37-loop of activated protein C modulate inhibition by protein C inhibitor but not by a(1)-antitrypsin.  Biochm. Biophys. Acata1649:106-117.

Hatada, S., Grant, D.J., and Maeda, N. (2003) An intronic endogenous retrovirus-like sequence attenuates human haptoglobin-related gene expression in an orientation-dependent manner.  Gene 319:55-63.

Hester, S., Benavides, G., Yoon, L., Morgan, K.T., Zou, F., Barry, W., and Wolf, D.C. (2003) Formaldehyde-induced gene expression in F344 rat nasal respiratory epithelium.  Toxicology187:13-24.

Hoffman, M., Loh, K.L., Bond, V.K., Palmieri, D., Ryan, J.L., and Church, F.C. (2003) Localization of heparin cofactor II in injured human skin: A potential role in wound healing.  Exp. Mol. Pathol.75:109-118.

Hooth, M.J., McDorman, K.S., Hester, S.D., George, M.H., Brooks, L.R., Swank, A.E., and Wolf, D.C. (2003) The carcinogenic response of Tsc2 mutant Long Evans (Eker) rats to a mixture of drinking water disinfection by-products was less than additive. Toxicol. Science 69:322-331.

Jahn, J.E., Ricketts, S.L., and Coleman, W.B. (2003)  Identification of candidate liver tumor suppressor genes from human 11p11.2 by transcription mapping of microcell hybrid cell lines.  Int. J. Oncol. 22:1303-1310.

Kaufmann, W.K., Heffernan, T.P., Beaulieu, L.M., Doherty, S., Frank, A.R., Zhou, Y., Bryant, M.F., Zhou, T., Luche, D.D., Nikolaishvilli-Feinberg, N., Simpson, D.A., and Cordeiro-Stone, M. (2003) Caffeine and human DNA metabolism: The magic and the mystery. Mutation Research 532:85-102.

Kuziel, W.A., Dawson, T.C., Quinones, M., Garavito, E., Chenaux, G., Ahuja, S.S., Reddick, R.L., and Maeda, N. (2003) CCR5 deficiency is not protective in the early stages of atherogenesis in apoE knockout mice. Atherosclerosis167:25-32.

McDorman, K.S., Chandra, S., Hooth, M.J., Hester, S.D., Schoonhoven, R., and Wolf, D.C. (2003) Induction of transitional cell hyperplasia in the urinary bladder and aberrant crypt foci in the colon of rats treated with individual and a mixture of drinking water disinfection by-products. Toxicologic Pathology 31:235-242.

Nakamura, J., Asakura, S., Hester, S.D., de Murcia, G., Caldecott, K.W., and Swenberg, J.A. (2003) Quantitation of intracellular NAD(P)H can monitor an imbalance of DNA single strand break repair in base excision repair defecient cells in real time.  Nucleic Acids Res. 31:e104.

Olsen, E.H., McCain, A.S., Merricks, E.P., Fischer, T.H., Dillon, I.M., Raymer, R.A., Bellinger, D.A., Fahs, S.A., Montgomery, R.R., Keith, J.C., Jr., Schaub, R.G., and Nichols, T.C. (2003) Comparative response of plasma VWF in dogs to up-regulation of VWF mRNA by interleukin-11 versus Weibel-Palade body release by desmopressin (DDAVP). Blood 102:436-441.

Pye, J., Ardeshirpour, F., McCain, A., Bellinger, D.A., Merricks, E., Adams, J., Elliott, P.J., Pien, C., Fischer, T.H., Baldwin, A.S., Jr., and Nichols, T.C. (2003)  Proteasome inhibition ablates activation of NF-kappa B in myocardial reperfusion and reduces reperfusion injury. Am. J. Physiol. Heart Circ. Physiol. 284:H919-926.

Rathore, V., Stapleton, M.A., Hillery, C.A., Montgomery, R.R., Nichols, T.C., Merricks, E.P., Newman, D.K., and Newman, P.J. (2003) PECAM-1 negatively regulates GPIb/V/IX signaling in murine platelets. Blood 102:3658-3664.

Ricketts, S.L., Carter, J.C., and Coleman, W.B. (2003) Identification of three 11p11.2 candidate liver tumor suppressors through analysis of known human genes.  Mol. Carcinogenesis 36:90-99.

Russell, K.E., Olsen, E.H., Raymer, R.A., Merricks, E.P., Bellinger, D.A., Read, M.S., Rup, B.J., Keith, J.C., Jr., McCarthy, K.P., Schaub, R.G., and Nichols, T.C. (2003) Reduced bleeding events with subcutaneous administration of recombinant human factor IX in immune-tolerant hemophilia B dogs. Blood 102:4393-4398.

Sediva, A., Bartunkova, J., Bartosova, J., Jennette, J.C., Falk, R.J., and Jethwa, H.S. (2003) Antineutrophil cytoplasmic antibodies directed against bactericidal/permeability-increasing protein detected in children with cystic fibrosis inhibit neutrophil-mediated killing of Pseudomonas aeruginosa.  Microbes Infect. 5:27-30.

Sundberg, L.J., Galante, L.M., Bill, H.M., Mack, C.P., and Taylor, J.M. (2003) An endogenous inhibitor of focal adhesion kinase blocks Rac1/JNK- but not Ras/ERK-dependent signaling in vascular smooth muscle cells.  J. Biol. Chem. 278:29783-29791.

Yamada, N.A., Castro, A., and Farber, R.A. (2003) Variation in the extent of microsatellite instability in human cell lines with defects in different mismatch repair genes. Mutagenesis18:277-282.

Yamada, N.A., Parker, J.M., and Farber, R.A. (2003) Mutation frequency analysis of mononucleotide and dinucleotide repaeats after oxidative stress.  Environ. Mol. Mutagenesis42:75-84.

Arnold, J.T., Lessey, B.A., Seppala, M., and Kaufman, D.G. (2002) Effect of normal endometrial stroma on growth and differentiation in Ishikawa endometrial adenocarcinoma cells. Cancer Res. 62:79-88.

Betz, B.L., Strobeck, M.W., Reisman, D.N., Knudsen, E.S., and Weissman, B.E. (2002) Re-expression of hSNF5/INI1/BAF47 in pediatric tumor cells leads to G1 arrest associated with induction of p16ink4a and activation of RB.  Oncogene21:5193-5203.

Boyer. J.C., Yamada. N.A., Roques, C.N., Hatch, S.B., Riess, K., and Farber, R.A. (2002) Sequence dependent instability of mononucleotide microsatellites in cultured mismatch repair proficient and deficient mammalian cells. Human Molecular Genetics 11:707-13.

Deming, P.B., Flores, K.G., Downes, C.S., Paules, R.S., and Kaufmann, W.K. (2003) ATR enforces the topoisomerase II-dependent G2 checkpoint through inhibition of Plk1 kinase. J. Biol. Chem. 277:36832-36838.

Fischer, T.H., Merricks, E.P., Bode, A.P., Bellinger, D.A., Russell, K., Reddick, R., Sanders, W.E., Nichols, T.C., and Read, M.S. (2002) Thrombus formation with rehydrated, lyophilized platlets.  Hematology 6:359-369.

Garg, R., Oliver, P.M., Maeda, N., and Pandey, K.N. (2002) Genomic structure, organization and promoter region analysis of murine guanylyl cyclase/atrial natriuretic peptide receptor-A gene.  Gene 291:123-133.

Gordon, G.J., Butz, G.M., Grisham, J.W., and Coleman, W.B. (2002)  Isolation, culture, and transplantation of small hepatocyte-like progenitor cells obtained retrorsine-exposed rats. Transplantation73:1236-1243.

Heffernan, T.P., Simpson, D.A., Frank, A.R., Heinloth, A.N., Paules, R.S., Cordiero-Stone, M., and Kaufmann, W.K. (2002) An ATR- and Chk1-dependent S checkpoint ibhibits replicon initiation following UVC-induced DNA damage.  Mol. Cell. Biol. 22:8552-8561.

Hester, S., Benavides, G., Sartor, M., Yoon, L., Wolf, D., and Morgan, K. (2002) Normal gene expression in male F344 rat nasal transitional/respiratory epithelium. Gene285:301-310.

Hodgin, J.B., and Maeda, N. (2002) Minireview: Estrogen and mouse models of atherosclerosis. Endocrinology143:4495-4501.

Hodgin, J.B., Knowles, J.W., Kim, H.S., Smithies, O., and Maeda, N. (2002) Interactions between endothelial nitric oxide ssynthase and sex hormones in vascular protection in mice. J. Clin. Invest. 109:541-548.

Hogan, K.A., Weiler-Guettler, H., and Lord, S.T. (2002) Mouse models in coagulation.  Thromb. Haemost. 87:563-574.

Hooth, M.J., McDorman, K.S., Hester, S.D., George, M.H., Brooks, L.R., Swank, A.E., and Wolf, D.C. (2002) The carcinogenic response of Tsc2 mutant Long Evans (Eker) rats to a mixture of drinking water disinfection by-products was less than additive. Toxicol. Sci. 69:322-331.

Kaufmann, W.K., Campbell, C.B., Simpson, D.A., Deming, P.B., Filatov, L., Galloway, D.S., Zhao, X.J., Creighton, A.M., and Downes, C.S. (2002) Degradation of ATM-independent decatenation checkpoint function in human cells is secondary to inactivation of p53 and correlated with chromosomal destabilization.  Cell Cycle 1:323-330.

Klinger, J.R., Warburton, R.R., Pietras, L., Oliver, P., Fox, J., Smithies, O., and Hill, N.S. (2002) Targeted disruption of the gene for natriuretic peptide receptor-A worsens hypoxia-induced cardiac hypertrophy.  Am. J. Physiol. Heart Circ. Physiol.282:H58-H65.

McDougall, K.E., Perry, M.J., Gibson, R.L., Bright, J.M., Colley, S.M., Hodgin, J.B., Smithies, O., and Tobias, J.H. (2002) Estrogen-induced osteogenesis in intact female mice lacking ERb.  Am. J. Physiol - Endocrinol. Metabolism 283:E817-E823.

Mitchell, J.W., Church, F.C. (2002) Aspartic acid residues 72 and 75 and tyrosine-sulfate 73 of heparin cofactor II promote intramolecular interactions during glycosaminoglycan binding and thrombin inhibition. J. Biol. Chem. 277:19823-19830.

Nyska, A., Hester, S.D., Cooper, R.L., Goldman, J.M., Stoker, T.E., House, D., and Wolf, D.C. (2002) Single or group housing-altered hormonal physiology and affected pituitary and interstitial cell kinetics.  J. Toxicol. Sci. 27:449-457.

Palmieri, D., Lee, J.-W., Juliano, R.L., and Church, F.C. (2002) Expression of plasminogen activator inhibitor-type 1 and 3increase cell adhesion and motility of MDA-MB-435 cancer cells.  J. Biol. Chem. 277:40950-40957.

Pereira, A.S., Kenney, K.B., Cohen, M.S., Eron, J.J., Tidwell, R.R., and Dunn, J.A. (2002)  Determination of amprenavir, a HIV-1 protease inhibitor, in human seminal plasma using high-performance liquid chromatography-tandem mass spectrometry.  J. Chromatography B Anal. Technol. Biomed. Life Sci. 766:307-317.

Pereira, A.S., Smeaton, L.M., Gerber, J.G., Acosta, E.P., Snyder, S., Fiscus, S.A., Tidwell, R.R., Gulick, R.M., Murphy, R.L., and Eron Jr., J.J. (2002)  The pharmacokinetics of amprenavir, zidovudine, and lamivudine in the genital tracts of men infected with human immunodeficiency virus type 1 (AIDS clinical trials group study of 850).  J. Infectious Diseases 186:198-204.

Preston, G.A., Zarella, C.S., Pendergraft, W.F., Rudolph, E.H., Yang, J.J., Sekura, S.B., Jennette, J.C., and Falk, R.J. (2002) Proteinase 3 and elastase: Novel effects of neutrophil-derived proteinase 3 and elastase on vascular endothelium involve in vivo cleavage of NF-kB and proapoptotic changes in JNK, ERK, and p38 MapK signaling pathways. J. Am. Soc. Nephrol. 13:2840-2849.

Reisman, D.N., Strobeck, M.W., Betz, B.L., Sciariotta, J., Funkhouser, W., Murchardt, C., Yaniv, M., Sherman, L.S., Knudsen, E.S., and Weissman, B.E., (2002) Concomitant down-regulation of BRM and BRG1 in human tumor cell lines: Differential effects on RB-mediated growth arrest versus CD44 expression.  Oncogene 21:1196-1207.

Remijn, J.A., Ijsseldijk, M.J., van Hemel, B.M., Galanakis, D.K., Hogan, K.A., Lounes, K.C., Lord, S.T., Sixma, J.J., and deGroot, P.G. (2002) Reduced platelet adhesion in flowing blood to fibrinogen by alterations in segment gamma316-322, part of the fibrin-specific region.  Br. J. Haematol. 117:650-657.

Ricketts, S.L., Garcia, N.F., Betz, B.L., and Coleman, W.B. (2002) Identification of candidate liver tumor suppressor genes from human 11p11.2-p12. Genes Chromosomes Cancer33:47-59.

Rider, M.A., Butz, G.M., Ricketts, S.L., Newberry, S.T., Grisham, J.W., and Coleman, W.B. (2002) Suppression of tumorigenicity in rat liver tumor cells by human chromosome 13: Evidence against the involvement of pRb and BRCA2. Int. J. Oncol. 20:235-245.

Strobeck, M.W., Reisman, D.N., Gunawardena, R.W., Betz, B.L., Angus, S.P., Knudsen, K.E., Kowalik, T.F., Weissman, B.E., and Knudsen, E.S. (2002) Compensation of BRG-1 function by BRM: Insight into the role of the core SWI/SNF subunits in RB-signaling.  J. Biol. Chem. 277:4782-4789.

Swardson-Olver, C.J., Dawson, T.C., Burnett, R.C., Peiper, S.C., Maeda, N., and Avery, A.C. (2002) Plasmodium yoelii uss the murine Duffy antigen receptor for chemokines as a receptor for normocyte invasion ansd an alternative receptor for reticulocyt invasion.  Blood 99:2677-2684.

Yamada, N.A., Smith, G.A., Castro, A., Roques, C.N., Boyer, J.C., and Farber, R.A. (2002) Relative rates of insertion and deletion mutations in dinucleotide repeats of various lengths in mismatch repair proficient mouse and mismatch repair deficient human cells.  Mutation Research 499:213-225.

Yamada, N.A. and Farber, R.A. (2002) Induction of a low level of microsatellite instability by overexpression of DNA polymerase beta.  Cancer Research 62:6061-6064.

Zhu, Y., Bian, Z., Lu, P., Karas, R.H., Bao, L., Cox, D., Hodgin, J., Shaul, P.W., Thoren, P., Smithies, O., Gustafsson, J.A., and Mendelsohn, M.E. (2002) Abnormal vascular function and hypertension in mice deficient in estrogen receptor beta.  Science295:505-508.

BaSalamah, M.A., Marr, H.S., Duncan, A.W., and Edgell, C.J. (2001) Testican in human blood. Biochem. Biophys. Res. Commun. 283:1083-1090.

Bauman, S.J., Whinna, H.C., and Church, F.C. (2001) Serpins (serine protease inhibitors).  Curr. Protocols Protein Science Unit 21.10.1-7. 

Bullock, S.K., Kaufmann, W.K., and Cordiero-Stone, M. (2001) Enhanced S phase delay and inhibition of replication of an undamaged shuttle vector in UVC-irradiated xeroderma pigmentosum variant.  Carcinogenesis 22:233-244.

DeCristofaro, M.F., Betz, B.L., Rorie, C.J., Reisman, D.N., Wang, W., and Weissman, B.E. (2001) Characterization of SWI/SNF protein expression in human breast cancer cell lines and other malignancies.  Journal of Cellular Physiology186:136-145.

Deming, P.B., Cistulli, C.A., Zhao, H., Graves, P.R., Piwnica-Worms, H., Paules, R.S., Downes, C.S., and Kaufmann, W.K. (2001) The human decatenation checkpoint. Proc. Natl. Acad. Sci. U.S.A. 98:12044-12049.

Goy, M.F., Oliver, P.M., Purdy, K.E., Knowles, J.W., Fox, J.E., Mohler, P.J., Qian, X., Smithies, O., and Maeda, N. (2001) Evidence for a novel natriuretic peptide receptor that prefers brain natriuretic peptide over atrial natriuretic peptide.  Biochem. J. 358:379-387.

Hodgin, J.B., Krege, J.H., Reddick, R.L., Korach, K.S., Smithies, O., and Maeda, N. (2001) Estrogen receptor alpha is a major mediator of 17beta-estradiol's atheroprotective effects on lesion size in Apoe-/- mice. J. Clin. Invest. 107:333-40.

Hogan, K.A., Maeda, N., Kluckman, K.D., Lord, S.T. (2001) Synthesis of a mouse model of the dysfibrinogen Vlissingen/Frankfurt IV.  Ann. N.Y. Acad. Sci. 936:117-121.

Hogan, K.A., Bolliger, B., Okumura, N., Lord, S.T. (2001) The formation of b fibrin requires a functional “a” site.  Ann. N.Y. Acad. Sci. 936:219-222.

Jordan, H.L., Pereira, A.S., Cohen, M.S., and Kashuba, A.D. (2001) Domestic cat model for predicting human nucleoside analogue pharmacokinetics in blood and seminal plasma.  Antimicrob. Agents Chemother. 45:2173-2176.

Kaufmann, W.K., Behe, C.I., Golubovskaya, V.M., Byrd, L.L., Albright, C.D., Borchert, K.M., Presnell, S.C., Coleman, W.B., Grisham, J.W., and Smith, G.J. (2001) Aberrant cell cycle checkpoint function in transformed hepatocytes and WB-F344 hepatic epithelial stem-like cells.  Carcinogenesis 22:1257-1269.

Knouff, C., Malloy, S., Wilder, J., Altenburg, M.K., and Maeda, N. (2001)  Doubling expression of the low density lipoprotein receptor by truncation of the 3’-untranslated region sequence ameliorates type III hyperlipoproteinemia in mice expressing the human ApoE2 isoform. J. Biol. Chem. 276:3856-3862.

Lawrence, D.W. and Pryzwansky, K.B. (2001) The vasodilator-stimulated phosphoproteins is regulated by cyclic GMP-dependent protein kinase during neutrophil spreading.  J. Immunology 166:5550-5556.

Lounes, K.C., Okumura, N., Hogan, K.A., Lord, S.T. (2001)  The polymerization site “a” function depends on the structural integrity of its nearby calcium-binding site. Ann. N.Y. Acad. Sci.  936:205-209.

Pereira, A.S., and Tidwell, R.R. (2001) Separation methods for nucleoside analogues used for treatment of HIV-1 infection.  J. Chromatography B Biomed. Sci. Applications 764:327-347.

Remijn, J.A. Lounes, K.C., Hogan, K.A., Lord, S.T., Galanakis, D.K., Sixma, J.J., and de Groot, P.G. (2001) Mutations on Fibrinogen (g316-322) are associated with reduction in platelet adhesion under flow conditions. Ann. N.Y. Acad. Sci. 936:444-448.

Taylor, S. and Pereira, A.S. (2001) Antiretroviral drug concentrations in semen of HIV-1 infected men. J. Infect. Dis. 77:4-11.

Yang J.J., Preston G.A., Pendergraft W.F., Segelmark M., Heeringa P., Hogan S.L., Jennette J.C., and Falk R.J. (2001) Internalization of proteinase 3 is concomitant with endothelial cell apoptosis and internalization of myeloperoxidase with generation of intracellular oxidants. Am. J. Pathol. 158:581-592.

Bush, E., Maeda, N., Kuziel, W.A., Dawson, T.C., Wilcox, J.N., DeLeon, H., and Taylor, W.R. (2000) CC cehemokine receptor 2 is required for macrophage infiltration and vascular hypertrophy in angiotension II-induced hypertension.  Hypertension36:360-363.

Bushman, J.E., Palmieri, D., Whinna, H.C., and Church, F.C. (2000) Insight into the mechanism of asparaginase-induced depletion of antithrombin III in treatment of childhood acute lymphoblastic leukemia.  Leukemia Research 27:559-565.

Dawson, T.C., Beck, M.A., Kuziel, W.A., Henderson, F., and Maeda, N. (2000) Contrasting effects of CCR5 and CCR2 deficiency in the pulmonary inflammatory response to influenza A virus.  American Journal of Pathology 156:1951-1959.

Dawson, T.C., Lentsch, A.B., Wang, Z., Cowhig, J.E., Rot, A., Maeda, N., and Peiper, S.C. (2000) Exaggerated response to endotoxin in mice lacking the Duffy antigen/receptr for chemokines (DARC).  Blood96:1681-1684.

Gordon, G.J., Coleman, W.B., Hixson, D.C., and Grisham, J.W. (2000)  Liver regeneration in rats with retrorsine-induced hepatocellular injury reveals the existence of a novel liver progenitor cell population.  American Journal of Pathology156:607-619.

Gordon, G.J., Coleman, W.B., and Grisham, J.W. (2000) Induction of cytochrome P450 enzymes in the livers of rats treated with the pyrrolizidine alkaloid retrorsine.  Experimental and  Molecular Patholology69:17-26.

Gordon, G.J., Coleman, W.B., and Grisham, J.W. (2000) Bax-mediated apoptosis in the livers of rats after partial hepatectomy in the retrorsine model of hepatocellular injury.  Hepatology32:312-320.

Gordon, G.J., Coleman, W.B., and Grisham, J.W. (2000) Temporal analysis of hepatocyte differentiation by small hepatocyte-like progenitor cells during liver regeneration in retrorsine-exposed rats. American Journal of Patholology 157:771-786.

Hogan, K.A., Lord, S.T., Okumura, N., Terasawa, F., Galanakis^, D.K., Scharrer, I., Gorkun, O.V.A (2000) Functional assay suggests that heterodimers exist in two C-terminal g-chain dysfibrinogens: Matsumoto I and Vlissingen/Frankfurt IV. Thrombosis and Hemostasis83:592-597.

Hogan, K.A., Gorkun, O.V., Lounes, K.C., Coates, A., Weisel, J.W., Hantgan, R.R., and Lord, S.T. (2000) Recombinant fibrinogen Vlissingen/Frankfurt IV: The deletion of residues 319 and 320 from the g-chain of fibrinogen alters calcium binding, fibrin, polymerization, cross-linking, and platelet aggregation. Journal of Biological Chemistry 275:17778-17785.

Holland, C.A., Henry, A.T., Whinna, H.C., and Church, F.C. (2000) Effect of oligodeoxynucleotide thrombin aptamer on thrombin inhibition by heparin cofactor II and antithrombin.  FEBS Lett. 484:87-91.

Jethwa, H.S., Nachman, P.H., Falk, R.J., and Jennette, J.C. (2000) False-positive myeloperoxidase binding activity due to DNA/anti-DNA antibody complexes: A source for analytical error in serologic evaluation of anti-neutrophil cytoplasmic autoantibodies.  Clin. Exp. Immunol. 121:544-550.

Jethwa, H.S., Clarke, S.H., Itoh-Lindstrom, Y., GFalk, R.J., Jennette, J.C., and Nachman, P.H. (2000) Restriction in V kappa gene use and antigen selection in anti-myeloperoxidase response in mice.  J. Immunol. 165:3890-3897.

Marr, H.S., BaSalamah, M.A., Bouldin, T.W., Duncan, A.W., and Edgell, C.J. (2000) Distribution of testican expression in human brain. Cell Tissue Res. 302:139-144.

Patel, A.C., Anna, C.H., Foley, J.F., Stockton, P.S., Tyson, F.L., Barrett, J.C., and Devereux, T.R. (2000) Hypermethylation of the p16(Ink4a) promoter in B6C3F1 mouse primary lung adenocarcinomas and mouse lung cell lines.  Carcinogenesis 21:1691-1700.

Pendergraft, W.F., Alcorta, D.A., Segelmark, M., Yang, J.J., Tuttle, R., Jennette, J.C., Falk, R.J., and Preston, G.A. (2000) ANCA antigens, proteinase 3 (PR3) and myeloperoxidase (MPO), are not expressed in endothelial cells.  Kidney International 57:1981-1990.

Pereira, A.S., Kenney, K.B., Cohen, M.S., Hall, J.E., Eron, J.J., Tidwell, R.R., and Dunn, J.A. (2000) Simultaneous determination of Lamivudine and Zidovudine concentrations in human seminal plasma using high performance liquid chromatography and tandem mass spectrometry.  Journal of Chromatography-B 742:173-183.

Segelmark, M., Barrett, C.V., Pendergraft, W.F., Falk, R.J., and Preston, G.A. (2000) Expression of p300-truncated fragments results in the modulation of apoptosis in rat mesangial cells. Kidney International 57:1873-1881.

Shirk, R.A., Parthasarathy, N., San Antonio, J.D., Church, F.C., and Wagner, W.D. (2000) Altered dermatan sulfate structure and reduced heparin cofactor II-stimulating activity of biglycan and decorin from human atherosclerotic plaque.  J. Biol. Chem. 275:18085-18092.

Yasuda, O., Zhang, S.H., Miyamoto, Y., Maeda, N. (2000) Differential expression of the alpha1 type VIII collagen gene by smooth muscle cells from atherosclerotic plaques of apolipoprotein-E-deficient mice. J. Vasc. Res. 37:158-169.

Bauman, S.J. and Church, F.C. (1999) Heparin cofactor II.  In: Laboratory Assays in Thrombosis - A Manual.  J. Jespersen, R.M. Bertina, and F. Havertake (Eds.) Kluwer Academic Publications, pp. 189-196.

Coleman W.B., Ricketts S.L., Borchert K.M., Presnell S.C., Esch G.L., McCullough K.D., Weissman B.E., Smith G.J., and Grisham J.W. (1999) Induction of rat WT1 gene expression correlates with human chromosome 11p11.2-p12-mediated suppression of tumorigenicity in rat liver epithelial tumor cell lines. International Journal of Oncology 14:957-963.

Dawson T.C., Kuziel W.A., Osahar T.A., and Maeda N. (1999) Absence of CC chemokine receptor-2 reduces atherosclerosis in apolipoprotein E-deficient mice. Atherosclerosis 143:205-211.

DeCristofaro, M.F., Betz, B.L., Wang, W., and Weissman, B.E. (1999) Alteration of hSNF5/INI1/BAF47 detected in rhabdoid cell lines and primary rhabdomyosarcomas but not Wilms' tumors. Oncogene 18:7559-7565.

Del Poeta, M., Toffaletti, D.L., Rude, T.H., Dykstra, C.C., Heitman, J., and Perfect, J.R. (1999) Tpoisomerase I is essential in Cryptococcusneoformans: Role in pathobiology and as an antifungal target. Genetics 152:167-178.

Golubovskaya, V.M., Filatov, L.V., Behe, C.I., Presnell, S.C., Hooth, M.J., Smith, G.J., and Kaufmann, W.K. (1999) Telomere shortening, telomerase expression, and chromosome instability in rat hepatic epithelial stem-like cells. Mol. Carcinogenesis 24:209-217.

Karas, R.H., Hodgin, J.B., Kwoun, M., Krege, J.H., Aronovitz, M., Mackey, W., Gustafsson, J.A., Korach, K.S., Smithies, O., Mendelsohn, M.E. (1999) Estrogen inhibits the vascular injury response in estrogen receptor beta-deficient female mice. Proc. Natl. Acad. Sci. U.S.A. 96:15133-15136.

Knouff, C., Hinsdale, M.E., Mezdour, H., Altenburg, M.K., Watanabe, M., Quarfordt, S.H., Sullivan, P.M., And Maeda, N. (1999) Apolipoprotein E structure determines VLDL clearance and atherosclerosis risk in mice. J. Clin. Invest. 103:1579-1586.

Lubin, I.M., Yamada, N.A., Stansel, R.M., Pace, R.G., Rohlfs, E.M., and Silverman, L.M. (1999) HFE genotyping using multiplex allele-specific polymerase chain reaction and capillary electrophoresis. Archives of Pathology and Laboratory Medicine 123:1177-1181.

Lyons-Darden, T. and Topal, M.D. (1999) Effects of temperature, Mg²⁺ concentration and mismatches on triplet-repeat expansion during DNA replication in vitro. Nucleic Acids Research27:2235-2240.

Lyons-Darden, T. and Topal, M.D. (1999) Abasic sites induce triplet-repeat expansion during DNA replication in vitro. Journal of Biological Chemistry 274:25975-25978.

Palmieri, D., Watson, J.M. and Rinehart, C.A. (1999) Age-related expression of PEDF/EPC-1 in human endometrial stromal fibroblasts: Implications for interactive senescence. Experimental Cell Research247:142-147.

Pandey, K.N., Oliver, P.M., Maeda, N., and Smithies, O. (1999) Hypertension associated with decreased testosterone levels in natriuretic peptide receptor-A gene-knockout and gene-duplicated mutant mouse models. Endocrinology140:5112-5119.

Pereira, A.S., Kashuba, A.D., Fiscus, S.A., Hall, J.E., Tidwell, R.R., Troiani, L., Dunn, J.A., Eron, J.J., Jr., and Cohen, M.S. (1999) Nucleoside analogues achieve high concentrations in seminal plasma: Relationship between drug concentration and virus burden. Journal of Infectious Diseases 180:2039-2043.

Rinehart, C.A., Watson, J.M., Torti, V.R., and Palmieri, D. (1999) The role of IL-1 in interactive senescence and age-related human endometrial cancer. Experimental Cell Research 248:599-607.

Wood, D.H., Hall, J.E., Rose, B.G., Boykin, D.W., and Tidwell, R.R. (1999) Pentamidine is a potent inhibitor of [³H]idazoxan binding to imidazoline I2 receptors.  Annals of the New York Acadaemy of Sciences 881:110-113.

Cistulli, C. A. and Kaufmann, W.K. (1998) P-53 dependent signaling is required for recovery of DNA replication and clonogenic survival in UVC-irradiated human fibroblasts. Cancer Research 58:1993-2002.

Filatov, L., Golubovskaya, V., Hurt, J.C., Byrd, L.L., Phillips, J.M., and Kaufmann, W.K. (1998) Chromosomal instability is correlated with telomere erosion and inactivation of G2 checkpoint function in human fibroblasts expressing human papillomavirus type 16 E6 oncoprotein. Oncogene16:1825-1838.

Isaacs, J.S., Harman, R., Carman, T.A., Barrett, J.C., and Weissman, B.E. (1998) Differential subcellular p53 localization and function in N- and S-type neuroblastoma cell lines.  Cell Growth Differentiation9:545-555.

Kazantsev, A., Bullock, S.K., Sancar, A., and Cordiero-Stone, M. (1998) Generation and characterization of an immortal cell line of xeroderma pigmentosum group E.  Mutation Research 407:55-65.

Krege, J.H., Hodgin, J.B., Couse, J.F., Enmark, E., Warner, M., Mahler, J.F., Sar, M., Korach, K.S., Gustafsson, J.A., and Smithies, O. (1998) Generation and reproductive phenotypes of mice lacking estrogen receptor beta. Proc. Natl. Acad. Sci. U.S.A. 95:15677-15682.

Marr, H.S., BaSalamah, M.A., Bouldin, T.W., Duncan, A.W., and Edgell, C.J.S. (1998)  Distribution of testican expression in human brain.  Cell Tissue Research 302:139-144.

McCullough, K.D., Coleman, W.B., Ricketts, S.L., Wilson, J.W., Smith, G.J., and Grisham, J.W. (1998) Plasticity of the neoplastic phenotype in vivo is regulated by epigenetic factors. Proceedings of the National Academy of Sciences USA 95:15333-15338.

Neese, L.L., Wolfe, C.A., and Church, F.C. (1998) Contribution of basic residues of the D and H helices in heparin binding to protein C inhibitor. Archives of Biochemistry and Biophysics 355:101-108.

Oliver, P.M., John, S.W., Purdy, K.E., Kim, R., Maeda, N., Goy, M.F., and Smithies, O. (1998) Natriuretic peptide receptor 1 expression influences blood pressures of mice in a dose-dependent manner.  Proc. Natl. Acad. Sci. U.S.A. 95:2547-2551.

Phillips, K.K., White, A.E., Hicks, D.J., Welch, D.R., Barrett, J.C., Wei, L.L., and Weissman, B.E. (1998) Correlation between reduction of metastasis in the MDA-MB-435 model system and increased expression of the Kai-1 protein. Mol. Carcinogenesis 21:111-120.

Reddick, R.L., Zhang, S.H., Maeda, N. (1998) Aortic atherosclerotic plaque injury in apolipoprotein E deficient mice. Atherosclerosis 140:297-305.

Wood, D.H., Hall, J.E., Rose, B.G., and Tidwell, R.R. (1998) 1,5-Bis(4-amidinophenoxy)pentane (pentamidine) is a potent inhibitor of [³H]idazoxan binding to imidazoline I2 binding sites. European Journal of Pharmacology 353:97-103.

Zhu, Z., Zhang, S.H., Wagner, C., Kurtz, A., Maeda, N., Coffman, T., Arendshorst, W.J. (1998) Angiotensin AT1B receptor mediates calcium signaling in vascular smooth muscle cells of AT1A receptor-deficient mice. Hypertension31:1171-1177.

Devereux, T.R., Anna, C.H., Patel, A.C., White, C.M., Festing, M.F., You, M. (1997) Smad (homolog of human DPC4) and Smad2 (homolog of human JV-18-1): Candidates for murine lung tumor resistance and suppressor genes. Carcinogenesis 18:1751-1755.

Isaacs, J.S., Chen, P., Garza, A., Hansen, M.F., Barrett, J.C., and Weissman, B.E. (1997) Failure of HPV E6 to rapidly degrade p53 in human HeLa x PNET cell hybrids. Oncogene 14:1669-1678. 

Kaufmann, W.K., Byrd, L.L., Palmieri, D., Nims, R.W. and J.M. Rice (1997) TGF-a sustains clonal expansion by promoter dependent, chemically initiated rat hepatocytes.Carcinogenesis18:1381-1387. 

Krege, J.H., Moyer, J.S., Langenbach, L.L., Peng, L., Zhang, S.H., Maeda, N., Reddick, R.L., and Smithies, O. (1997) Angiotensin-converting enzyme gene and atherosclerosis. Arterioscler. Thromb. Vasc. Biol. 17:1245-1250.

Kuziel, W.A., Morgan, S.J., Dawson, T.C., Griffin, S., Smithies, O., Ley, K., and Maeda, N. (1997) Severe reduction in leukocyte adhesion and monocyte extravasation in mice deficient in CC chemokine receptor 2. Proceedings of the National Academy of Sciences USA 94:12053-12058.

Marr, H.S., BaSalamah, M.A., and Edgell, C.J.S. (1997) Endothelial cell expression of testican mRNA.  Endothelium J. Endothelial Cell Res. 5:209-219. 

Oliver, P.M., Fox, J.E., Kim, R., Rockman, H.A., Kim, H.S., Reddick, R.L., Pandey, K.N., Milgram, S.L., Smithies, O., and Maeda, N. (1997) Hypertension, cardiac hypertrophy, and sudden death in mice lacking natriuretic peptide receptor A. Proc. Natl. Acad. Sci. U.S.A. 94:14730-14735. 

Reid, L.H., Davies, C., Cooper, P.R., Crider-Miller, S.J., Sait, S.N., Nowak, N.J., Evans G., Stanbridge, E.J., deJong, P., Shows, T.B., Weissman, B.E., and Higgins, M.J. (1997) A 1-Mb physical map and PAC contig of the imprinted domain in 11p15.5 that contains TAPA1 and the BWSCR1/WT2 region. Genomics 43:366-375. 

Reinhart, C.A., and Torti, V.R. (1997) Aging and cancer: The role of stromal interactions with epithelial cells.  Molecular Carcinogenesis 18:187-192. 

Yang, X., Welch, D.R., Phillips, K.K., Weissman, B.E., and Wei, L.L. (1997) KAI1, a putative marker for metastatic potential in human breast cancer. Cancer Lett. 119:149-155. 

Zhang, S.H., Reddick, R.L., Avdievich, E., Surles, L.K., Jones, R.G., Reynolds, J.B., Quarfordt, S.H., and Maeda, N. (1997) Paradoxical enhancement of atheroschlerosis by probucol treatment in apolipoprotein E-deficient mice.  J. Clin. Invest. 99:2858-2866.

Lee, J.H., Miele, M.E., Hicks, D.J., Phillips, K.K., Trent, J.M., Weissman, B.E., and Welch, D.R. (1996) KiSS-1, a novel human malignant melanoma metastasis-suppressor gene.  J. Natl. Cancer Inst.88:1731-1737.

Orlow, I., Iavarone, A., Crider-Miller, S.J., Bonilla, F., Latres, E., Lee, M.H., Gerald, W.L., Massague, J., Weissman, B.E., and Cordon-Cardo, C. (1996) Cyclin-dependent kinase inhibitor p57KIP2 in soft tissue sarcomas and Wilms' tumors. Cancer Res. 56:1219-1221.

Phillips, K.K., Welch, D.R., Miele, M.E., Lee, J.H., Wei, L.L., and Weissman, B.E. (1996) Suppression of MDA-MB-435 breast carcinoma cell metastasis following the introduction of human chromosome 11. Cancer Res. 56:1222-1227

Randell, S.H., Liu, J.Y., Ferriola, P.C., Kaartinen, L., Doherty, M.M., Davis, C.W., and Nettesheim, P. (1996) Mucin production by SPOC1 cells – An immortalized rat tracheal epithelial cell line.  Am. J. Respir. Cell. Mol. Biol. 14:146-154.

Reid, L.H., West, A., Gioeli, D.G., Phillips, K.K., Kelleher, K.F., Araujo, D., Stanbridge E.J., Dowdy, S.F., Gerhard, D.S., and Weissman, B.E. (1996) Localization of a tumor suppressor gene in 11p15.5 using the G401 Wilms' tumor assay. Human Mol. Genetics 5:239-247.

Reid, L.H., Crider-Miller, S.J., West, A., Lee, M.H., Massague, J., and Weissman, B.E. (1996) Genomic organization of the human p57KIP2 gene and its analysis in the G401 Wilms' tumor assay. Cancer Res.56:1214-1218.

Shirk, R.A., Church, F.C., and Wagner, W.D. (1996)  Arterial smooth muscle cell heparan sulfate proteoglycans accelerate thrombin inhibition by heparin cofactor II.  Arteriosclerosis Thrombosis Vascular Biology 16:1138-1146.

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Chen, P., Lin, H.H., and Weissman, B.E. (1995) A functional analysis of tumor suppressor activity for peripheral neuroepitheliomas by monochromosome transfer. Oncogene 10:577-586.

Chiao, C., Zhang, Y., Kaufman, D.G., and Kaufmann, W.K. (1995) Phenobarbital modulates the type of cell death by rat hepatocytes during deprivation of serum in vitro.  Hepatology22:297-303.

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Feingold, K.R., Elias, P.M., Mao-Qiang, M., Fartasch, M., Zhang, S.H., and Maeda, N. (1995) Apolipoprotein E deficiency leads to cutaneous foam cell formation in mice. J. Invest. Dermatol. 104:246-250.

Goodrum, J.F., Bouldin, T.W., Zhang, S.H., Maeda, N., and Popko, B. (1995) Nerve regeneration and cholesterol reutilization occur in the absence of apolipoproteins E and A-I in mice. J. Neurochem. 64:408-416.

Homanics, G.E., de Silva, H.V., Osada, J., Zhang, S.H., Wong, H., Borensztajn, J., and Maeda, N. (1995) Mild dyslipidemia in mice following targeted inactivation of the hepatic lipase gene. J. Biol. Chem. 270:2974-2980.

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Miller, R.T., Cattley, R.C., Marsman, D.S., Lyght, O., and Popp, J.A. (1995) TGFalpha differentially expressed in liver foci induced by diethylnitrosamine initiation and peroxisome proliferator promotion. Carcinogenesis16:77-82.

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Cattley, R.C., Kato, M., Popp, J.A., Teets, V.J., and Voss, K.S. (1994) Initiator-specific promotion of hepatocarcinogenesis by WY-14,643 and clofibrate. Carcinogenesis 15:1763-1766.

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Marsman, D.S. and Popp, J.A. (1994) Biological potential of basophilic hepatocellular foci and hepatic adenoma induced by the peroxisome proliferator, Wy-14,643. Carcinogenesis 15:111-117.

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Welch, D.R., Chen, P., Miele, M.E., McGary, C.T., Bower, J.M., Stanbridge, E.J., and Weissman, B.E. (1994) Microcell-mediated transfer of chromosome 6 into metastatic human C8161 melanoma cells suppresses metastasis but does not inhibit tumorigenicity. Oncogene 9:255-262.

Zhang, S.H., Reddick, R.L., Burkey, B., and Maeda, N. (1994) Diet-induced atherosclerosis in mice heterozygous and homozygous for apolipoprotein E gene disruption. J. Clin. Invest. 94:937-945.

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Keller, B.J., Bradford, B.U., Marsman, D.S., Cattley, R.C., Popp, J.A., Bojes, H.K., and Thurman, R.G. (1993) The nongenotoxic hepatocarcinogen Wy-14,643 is an uncoupler of oxidative phosphorylation in vivo. Toxicol. Appl. Pharmacol. 119:52-58.

Lincoln, T.M., Pryzwansky, K.B., Cornwell, T.L., Wyatt, T.A., MacMillan, L.A. (1993) Cyclic-GMP-dependent protein kinase in smooth muscle and neutrophils.  Adv. Second Messenger Phosphoprotein Res. 28:121-132.

Marsman, D.S., Swanson-Pfeiffer, C.L., and Popp, J.A. (1993) Lack of comitogenicity by the peroxisome proliferator hepatocarcinogens, Wy-14,643 and clofibric acid. Toxicol. Appl. Pharmacol. 122:1-6.

Phillips, J.E., Shirk, R.A., Whinna, H.C., Henriksen, R.A., and Church, F.C. (1993) Inhibition of dysthrombins Quick I and II by heparin cofactor II and antithrombin. Journal of Biological Chemistry 268:3321-3327.

Popko, B., Goodrum, J.F., Bouldin, T.W., Zhang, S.H., and Maeda, N. (1993) Nerve regeneration occurs in the absence of apolipoprotein E in mice. J. Neurochem. 60:1155-1158.

Whinna, H.C. and Church, F.C. (1993) Interaction of thrombin with antithrombin, heparin cofactor II, and protein C inhibitor.  Journal of Protein Chemistry 12:677-688.

Whinna, H.C., Choi, H.U., Rosenberg, L.C., and Church, F.C. (1993) Interaction of heparin cofactor II with biglycan and decorin.  Journal of Biological Chemistry268:3920-3924.

Wyatt, T.A., Lincoln, T.M., and Pryzwansky, K.B. (1993) Regulation of human neutrophil degranulation by LY83583 and L-arginine: The role of cGMP and cGMP-dependent protein kinase. Am. J. Physiol. 265:C201-C211.

Conway, K., Morgan, D., Phillips, K.K., Yuspa, S.H., and Weissman, B.E. (1992) Tumorigenic suppression of a human cutaneous squamous cell carcinoma cell line in the nude mouse skin graft assay. Cancer Res. 52:6487-6495.

Futreal, P.A., Barrett, J.C., and Wiseman, R.W. (1992) Dinucleotide repeat polymorphism in the THRA1 gene.  Human Mol. Genetics1:66.

Futreal, P.A., Soderkvist, P., Marks, J.R., Iglehart, J.D., Cochran, C., Barrett, J.C., and Wiseman, R.W. (1992)  Detection and frequent allelic loss on proximal chromosome 17q in sporadic breast carcinoma using microsatellite length polymorphisms.  Cancer Res. 52:2624-2627.

Keller, B.J., Marsman, D.S., Popp, J.A., and Thurman, R.G. (1992) Several nongenotoxic carcinogens uncouple mitochondrial oxidative phosphorylation. Biochim. Biophys. Acta 1102:237-244.

Marsman, D.S., Goldsworthy, T.L., and Popp, J.A. (1992) Contrasting hepatocytic peroxisome proliferation, lipofuscin accumulation and cell turnover for the hepatocarcinogens Wy-14,643 and clofibric acid. Carcinogenesis13:1011-1017.

McFarland, R.D., Vincent, J.L., and Smith, G.J. (1992) Isolation by fluorescence-activated cell sorting of cells of a human lymphoblastoid cell strain containing mutations in the lambda immunoglobulin gene. Environmental & Molecular Mutagenesis 19:297-303.

Piedrahita, J.A., Zhang, S.H., Hagaman, J.R., Oliver, P.M., and Maeda, N. (1992) Generation of mice carrying a mutant apolipoprotein E gene inactivated by gene targeting in embryonic stem cells. Proc. Natl. Acad. Sci. U.S.A. 89:4471-4475.

Pratt, C.W., Whinna, H.C., and Church, F.C. (1992) A comparison of three heparin-binding serine proteinase inhibitors.  Journal of Biological Chemistry 267:8795-8801.

Rogers, S.J., Pratt, C.W., Whinna, H.C., and Church, F.C. (1992) Role of thrombin exosites in inhibition by heparin cofactor II.  Journal of Biological Chemistry 267:3613-3617.

Wada, N., Marsman, D.S., and Popp, J.A. (1992) Dose-related effects of the hepatocarcinogen, Wy-14,643, on peroxisomes and cell replication. Fundamental Appl. Toxicol. 18:149-154.

Zhang, S.H., Reddick, R.L., Piedrahita, J.A., and Maeda, N. (1992) Spontaneous hypercholesterolemia and arterial lesions in mice lacking apolipoprotein E. Science 258:468-471.

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Futreal, P.A., Barrett, J.C., and Wiseman, R.W. (1991) An Alu polymorphism intragenic to the TP53 gene.  Nucleic Acids Res. 19:6977.

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Whinna, H.C., Blinder, M.A., Szewczyk, M., Tollefsen, D.M., and Church, F.C. (1991) Role of lysine 173 in heparin binding to heparin cofactor II.  Journal of Biological Chemistry 266:8129-8135.

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Cattley, R.C., Marsman, D.S., and Popp, J.A. (1990) Cell proliferation and promotion in the hepatocarcinogenicity of peroxisome proliferating chemicals. Prog. Clin. Biol. Res. 340D:123-132.

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Cattley, R.C., Marsman, D.S., and Popp, J.A. (1989) Failure of the peroxisome proliferator WY-14,643 to initiate growth-selectable foci in rat liver. Toxicology 56:1-7.

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