The training program is at UNC Hospitals, a tertiary care, academic medical center comprised of North Carolina Memorial Hospital, North Carolina Neurosciences Hospital, North Carolina Women's Hospital, and North Carolina Children's Hospital. The medical center has 688 beds and provides the pathology trainee with a broad case mix. The Anatomic and Clinical Pathology Services at UNC Hospitals are within the McLendon Clinical Laboratories. Anatomic Pathology services include Surgical Pathology, Cytopathology, the Autopsy Service, Neuropathology, Ophthalmic Pathology, the Histology Laboratory and the Electron Microscopy Service. Clinical Pathology (Laboratory Medicine) services include the Core Laboratory (which includes automated chemistry, hematology, and coagulation components), Microbiology, Immunology, Histocompatibility, Molecular Pathology, Clinical Chemistry, Hematology, and Transfusion Medicine (Blood Bank). In 2005, there were approximately 23,000 accessions in the surgical pathology laboratory, 23,000 accessions in the cytopathology laboratory, and over 4.5 million procedures in the clinical laboratories.

Chapel Hill has a population of approximately 49,000, including nearly 28,000 students, and is consistently ranked as one of the most desirable places to live in the US. Local recreational facilities supplement nearby state parks, and several large man-made lakes offer water sports. Chapel Hill is approximately halfway between the mountains and the coast of North Carolina. Several web sites focusing on the area are listed below.

The library, cultural and recreational facilities of the University are available to housestaff members. They may also purchase staff tickets to University intercollegiate athletic events. UNC and nearby Duke University and North Carolina State University have extensive programs of concerts, lectures, movies, and special events.